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Protein Overview: ptc-2

General Information:
Name(s) found: ptc-2 / CE36831 [WormBase]
Description(s) found:
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  • WBGene00004209 locus:ptc-2 status:Predicted UniProt:Q09540 protein_id:CCD66118.1 [WormBase]
  • gi|71987094|ref|NP_495218.2| PaTChed family member (ptc-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|52353912|gb|AAC46717.2| Patched family protein 2 [Caenorhabditis elegans] [NCBI NR]
  • Patched family protein 2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted TR:Q09540 protein_id:AAC46717.2 [wormpep150.fasta]
  • 36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted TR:Q09540 protein_id:AAC46717.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted TR:Q09540 protein_id:AAC46717.1 [wormpep132.fasta]
  • 36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted TR:Q09540 protein_id:AAC46717.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted UniProt:Q09540_CAEEL protein_id:AAC46717.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted UniProt:Q09540_CAEEL protein_id:AAC46717.2| [wormORF-contam.fasta]
  • PaTChed family member (ptc-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted UniProt:Q09540 protein_id:AAC46717.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE36831 WBGene00004209 locus:ptc-2 membrane protein patched (ptc) status:Predicted UniProt:Q09540 protein_id:CCD66118.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE36831 WBGene00004209 locus:ptc-2 status:Predicted UniProt:Q09540 protein_id:CCD66118.1 [wormpep246-ecoli-contam.fasta]
  • PaTChed family OS=Caenorhabditis elegans GN=ptc-2 PE=4 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 667 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: hedgehog receptor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENMYPQNV DYAAEMTGGC SGFASNVLNW PEDMILGNPR RAKKGGKLSG ADALQFVFLV  60
   61 ASPADVFLRF KQSLEETLET LSLYEEHCIH LHRHPLLICS RNSVNSTIPS SLLDMLSCWH 120
  121 MLLLLILDLT TAFRLQNHQW GFALAGVLVV TFASVAGIGL ATWFGIEFNA ATTQIVPFLT 180
  181 LGIGVDNMFM LLHNYRDVVK LAGGHAEMAI LMRETGMSIL CTSINNILSF LTGTLLPIPA 240
  241 LRSFCAQSSI LLTFNFIAIL TIYPAIISID LRRKKAQRRD FDTREESTSE ASIMQQFDGI 300
  301 TQAQMASSDD PAPWSLHSFI RYYYIPFISK PASKVAIIVG CCALLGASFV GMRQSTLGLE 360
  361 LGDVLPEHTA PAQFLRARDK YFSFYPMFAV IKGPNIDYAH QQRQIDNYRQ SIGSSKYVIK 420
  421 NKNEEPSEKY WLGLMRDWLI SIQRGFDEEV AKGSFNLTSG TVIGSNVSED ARLAHALMCS 480
  481 HGSLFECAGR IGKIRLIPFY LTGLTDTAVI VDAIKDIRSV CERFTDQGLP NFPQGIAFTF 540
  541 WEQYLFLTGN LMQAISIITI SVFCVISVLL FNPWAALMVV CILGIMTCEL AGFMGLVGIK 600
  601 LNPVSAVTLI TAVGIGVEFT VHVVVSFLTA LGTRSQRTSS AVDRVFVPVI HGSFSTLLGI 660
  661 LMLGFSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..523] PSI-BLAST 72.522879 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains; Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains; Multidrug efflux transporter AcrB transmembrane domain
    2 View Details [524..667] MSA 5.351994 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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