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Protein Overview: tag-72

General Information:
Name(s) found: tag-72 / CE36918 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00006447 locus:tag-72 mRNA cap guanine-N7 methyltransferase status:Confirmed UniProt:Q9XVS1 protein_id:CAB02758.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mRNA capping [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    Molecular Function: methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSEVASHY NKVLQVGIEG RKESRIFFMR NMNNWVKSQL INDAKQRVND NGVNNPRVLD  60
   61 LACGKGGDLK KWDIAGAKDV VMADVADVSI QQAEERYKQM FGYKKNNIFT VQFIVADCTK 120
  121 ENLEDRIENK DPFDLVSCQF ALHYSFVDEA SARIFLKNAV GMLKPGGVFI GTLPDADRIV 180
  181 WSMRNGENGQ FANEVCKITY ENVEELAEGK VPLFGAKFHF SLDEQVNCPE FLAYFPLVKH 240
  241 LLEELDMELL FVHNFAEAIN KWLEPGRRLL ESMTGLETYP NEKLSGKSDD EYLEAKAKLD 300
  301 AFPEDERIKT MGTLSKSEWE AICMYLVFGF RKKKSEAEKT EEEPATTKPV AESESEQKEV 360
  361 TESEEKEDQE DCEHQEAQTN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..380] PSI-BLAST 33.0 Structure and mechanism of mRNA cap (guanine N-7) methyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • mRNA (guanine-N7-)-methyltransferase activity
    		•  4.23788594273427 bayes_pls_golite062009
  • mRNA methyltransferase activity
    		•  4.23788594273427 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.50181720310228 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.39031546273566 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.30769384783609 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  2.26670816231281 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  1.86200407013263 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  1.3386061065513 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • RNA binding
    		•  1.10729923226801 bayes_pls_golite062009
  • transferase activity
    		•  1.07321114919891 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  0.868107614027708 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • binding
    		•  0.383237930789959 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle