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Protein Overview: cdc-14

General Information:
Name(s) found: cdc-14 / CE36916 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000383 locus:cdc-14 Probable tyrosine-protein phosphatase cdc-14 status:Confirmed UniProt:P81299 protein_id:CCD64955.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 707 amino acids

    Gene Ontology:
    Cellular Component: spindle [IDALink to PubMed article]
    midbody [IDALink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    protein amino acid dephosphorylation [IEALink to PubMed article]
    dephosphorylation [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    protein tyrosine phosphatase activity [IEALink to PubMed article]
    phosphatase activity [IEALink to PubMed article]
    protein tyrosine/serine/threonine phosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREDHSPRRN NTIENTLTEL LPNRLYFGCF PNPDAIDKSD KSVKKTCFIN INNKFHYEPF  60
   61 YEDFGPWNLS VLYRLCVQVG KLLEVEEKRS RRVVLFCQDD GTGQYDKIRV NTAYVLGAYL 120
  121 IIYQGFSADD AYLKVSSGET VKFVGFRDAS MGSPQYLLHL HDVLRGIEKA LKFGWLDFSD 180
  181 FDYEEYEFYE RVENGDFNWI IPGKILSFCG PHNESREENG YPYHAPDVYF DYFRENKVST 240
  241 IVRLNAKNYD ASKFTKAGFD HVDLFFIDGS TPSDEIMLKF IKVVDNTKGG VAVHCKAGLG 300
  301 RTGTLIACWM MKEYGLTAGE CMGWLRVCRP GSVIGPQQPY LIEKQKFCWS LSQSNGVHLT 360
  361 QNKEEKRNVR RLVNQVDDIN LGEERISPKS RENTRPNILR RRVQVQNGRS TAPVTIAPAG 420
  421 TSESRRSTKP SRVVDETALD DQGRSQGDRL LQLKAKHQHE SETTSPNSSS SRRFVKSSTP 480
  481 QMTVPSQAYL NRNREPIIVT PSKNGTSSGT SSRQLKTTPN GNVAYRTRNS SGNTTSTLTR 540
  541 TGNESYRFHN SLFYEPASAV FPSMASRRSE TTRYLSPTTP IKPMSPSYTD GTSPRYKARL 600
  601 RSENPIGSTT STPFSLQPQI TKCSLTAESK PPKRILSMPG TSKSTSSLKK IQVSRPRPYP 660
  661 STGVRVELCA NGKSYDIRPR KEAHVIPGAG LAANTEALLG KRRKTAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..360] PSI-BLAST 137.0 Proline directed phosphatase CDC14b2
    2 View Details [361..479] PSI-BLAST 44.154902 RPTP Lar
    3 View Details [480..593] deduced N/A No confident structure predictions are available.
    4 View Details [594..707] MSA 4.227996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphatase activity
    		•  0.478406022164162 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.45370611637567 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.372398769464001 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.354975426764985 bayes_pls_golite062009
  • hydrolase activity
    		•  0.346372799674989 bayes_pls_golite062009
  • catalytic activity
    		•  0.16233167791503 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle