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Protein Overview: MAM3_ARATH

General Information:
Name(s) found: MAM3_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|9759360|dbj|BAB09819.1| 2-isopropylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|75309227|sp|Q9FN52.1|MAM3_ARATH RecName: Full=Methylthioalkylmalate synthase 3, chloroplastic; AltName: Full=Methylthioalkylmalate synthase-like; AltName: Full=2-isopropylmalate synthase 2; Flags: Precursor [NCBI NR]
  • gi|38567506|emb|CAD31204.1| methylthioalkylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|38567504|emb|CAD31203.1| methylthioalkylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|38567498|emb|CAD31200.1| methylthioalkylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|38567488|emb|CAD31195.1| methylthioalkylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|31711914|gb|AAP68313.1| At5g23020 [Arabidopsis thaliana] [NCBI NR]
  • gi|20466167|gb|AAM20401.1| 2-isopropylmalate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15237196|ref|NP_197693.1| IMS2 (2-ISOPROPYLMALATE SYNTHASE 2); 2-isopropylmalate synthase/ methylthioalkylmalate synthase [Arabidopsis thaliana] [NCBI NR]
  • Methylthioalkylmalate synthase 3, chloroplastic OS=Arabidopsis thaliana GN=MAM3 PE=1 SV=1 [Swiss-Prot]
  • (Q9FN52) 2-isopropylmalate synthase-like protein (At5g23020) [athaliana3702.FASTAC.txt]
  • At5g23020 [Arabidopsis thaliana]gi|9759360|dbj|BAB09819.1| 2-isopropylmalate synthase-like protein [Arabidopsis thaliana]gi|38567506|emb|CAD31204.1| methylthioalkylmalate synthase-like protein [Arabidopsis thaliana]gi|38567504|emb|CAD31203.1| methylthi [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 2-isopropylmalate synthase 2 (IMS2) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: MAM-L, MAM3, IMS2 | IMS2/MAM-L/MAM3 (METHYLTHIOALKYMALATE SYNTHASE-LIKE); 2-isopropylmalate synthase/ methylthioalkylmalate synthase | chr5:7718206-7721637 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • methylthioalkylmalate synthase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At5g23020 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 2-isopropylmalate synthase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • MAM-L (METHYLTHIOALKYMALATE SYNTHASE-LIKE) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: MAM-L, MAM3, IMS2 | 2-isopropylmalate synthase 2 | chr5:7718203-7721634 FORWARD LENGTH=503 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 503 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: leucine biosynthetic process [TAS]
    glucosinolate biosynthetic process [IDA][IGI][IMP]
    Molecular Function: 2-isopropylmalate synthase activity [IGI][NAS]
    methylthioalkylmalate synthase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLLLTSSS MITTSCRSMV LRSGLPIGSS FPSLRLTRPY DKATLFVSCC SAESKKVATS  60
   61 ATDLKPIMER RPEYIPNKLP HKNYVRVLDT TLRDGEQSPG AALTPPQKLE IARQLAKLRV 120
  121 DIMEVGFPVS SEEEFEAIKT IAKTVGNEVD EETGYVPVIC GIARCKKRDI EATWEALKYA 180
  181 KRPRVMLFTS TSEIHMKYKL KKTKEEVIEM AVNSVKYAKS LGFKDIQFGC EDGGRTEKDF 240
  241 ICKILGESIK AGATTVGFAD TVGINMPQEF GELVAYVIEN TPGADDIVFA IHCHNDLGVA 300
  301 TANTISGICA GARQVEVTIN GIGERSGNAP LEEVVMALKC RGESLMDGVY TKIDSRQIMA 360
  361 TSKMVQEHTG MYVQPHKPIV GDNCFVHESG IHQDGILKNR STYEILSPED VGIVKSENSG 420
  421 IVLGKLSGRH AVKDRLKELG YEISDEKFND IFSRYRELTK DKKRITDADL KALVVNGAEI 480
  481 SSEKLNSKGI NDLMSSPQIS AVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..503] PSI-BLAST 94.0 Crystal Structure of LeuA from Mycobacterium tuberculosis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.67031204377352 bayes_pls_golite062009
  • 2-isopropylmalate synthase activity
    		•  2.51149699447745 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.36606715825952 bayes_pls_golite062009
  • porphobilinogen synthase activity
    		•  1.24455949903754 bayes_pls_golite062009
  • binding
    		•  1.1388634428163 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.891977953086329 bayes_pls_golite062009
  • lyase activity
    		•  0.740424046054758 bayes_pls_golite062009
  • transferase activity
    		•  0.464721888799972 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.36754360512349 bayes_pls_golite062009
  • transaldolase activity
    		•  0.184100272651834 bayes_pls_golite062009
  • fructose-bisphosphate aldolase activity
    		•  0.0818126250353252 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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