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Protein Overview: MCA8_ARATH

General Information:
Name(s) found: MCA8_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75265505|sp|Q9SA41.1|MCA8_ARATH RecName: Full=Metacaspase-8; Short=AtMC8 [NCBI NR]
  • gi|4966363|gb|AAD34694.1|AC006341_22 Similar to gb|AF098458 latex-abundant protein (LAR) from Hevea brasiliensis. [Arabidopsis thaliana] [NCBI NR]
  • gi|37788559|gb|AAP44521.1| metacaspase 8 precursor [Arabidopsis thaliana] [NCBI NR]
  • gi|32482822|gb|AAP84711.1| metacaspase 8 [Arabidopsis thaliana] [NCBI NR]
  • pir||E86299 F3O9.22 protein - Arabidopsis thaliana [NCBI NR]
  • gi|15219249|ref|NP_173092.1| MC8 (METACASPASE 8); cysteine-type endopeptidase [Arabidopsis thaliana] [NCBI NR]
  • Metacaspase-8 OS=Arabidopsis thaliana GN=AMC8 PE=1 SV=1 [Swiss-Prot]
  • (Q9SA41) F3O9.22 protein (Metacaspase 8) [athaliana3702.FASTAC.txt]
  • metacaspase 8 [Arabidopsis thaliana]gi|32482822|gb|AAP84711.1| metacaspase 8 [Arabidopsis thaliana]gi|4966363|gb|AAD34694.1| Similar to gb|AF098458 latex-abundant protein (LAR) from Hevea brasiliensis. [Arabidopsis thaliana]gi|25348268|pir||E86299 F3O9 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Latex-abundant protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATMC8 | ATMC8 (METACASPASE 8); caspase | chr1:5612298-5613823 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Similar to gb|AF098458 latex-abundant protein (LAR) from Hevea brasiliensis. [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • metacaspase 8 precursor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • metacaspase 8 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • caspase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATMC8, MC8 | metacaspase 8 | chr1:5612304-5613829 REVERSE LENGTH=381 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 381 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: response to oxidative stress [IEP][IMP]
    response to UV-C [IEP]
    response to hydrogen peroxide [IMP]
    programmed cell death [IMP]
    hydrogen peroxide-mediated programmed cell death [IMP]
    Molecular Function: cysteine-type endopeptidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKALLIGI NYPGTAVELR GCVNDVHRMQ KCLIELYGFA NKDIVIMIDT DKSCIQPTGK  60
   61 NICDELDNLI ASGQSGDFLV FHYSGHGTRI PPGIEDSEDP TGFDECITPC DMNLIKDQQF 120
  121 REMVSRVKEG CQLTIISDSC HSGGLIQEVK EQIGESHMKP VDKVKEQIEE SHMKQPKLGI 180
  181 ASYFLNIVMN LLATCGVSKS QRDRGGGEES FRGEIELEKD ETLDIKTRYL PFESYLSLLK 240
  241 EQTGQTNIEP VRIRQTLLKL FGEDPSPNRQ RGLSDLGNCE VDAGDSGASR LNAVTDNGIL 300
  301 LSGCQTDQRS EDVYVTRTGK AYGAFSDAIQ MILSAPRKDK KKITNKELVS EARVFLKKRG 360
  361 YSQRPGLYCH DRFVDKPFIC Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] PSI-BLAST 10.0 Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
    2 View Details [146..381] FFAS03 1.05 Caspase-9

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.446816200197746 bayes_pls_golite062009
  • binding
    		•  0.128865592323915 bayes_pls_golite062009
  • hydrolase activity
    		•  0.00345801703057891 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle