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Protein Overview: KHSE_ARATH

General Information:
Name(s) found: KHSE_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7532410|gb|AAF63224.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana] [NCBI NR]
  • gi|24899693|gb|AAN65061.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana] [NCBI NR]
  • gi|22135868|gb|AAM91516.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana] [NCBI NR]
  • gi|15227800|ref|NP_179318.1| HSK (HOMOSERINE KINASE); homoserine kinase [Arabidopsis thaliana] [NCBI NR]
  • Homoserine kinase OS=Arabidopsis thaliana GN=HSK PE=1 SV=1 [Swiss-Prot]
  • (Q8L7R2) 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (Putative homoserine kinase HSK) [athaliana3702.FASTAC.txt]
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana]gi|7532410|gb|AAF63224.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana]gi|15227800|ref|NP_179318.1| homoserine kinase (HSK) [Arabidopsis thaliana]gi|2489 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Homoserine kinase (HSK) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: HSK | HSK (HOMOSERINE KINASE); homoserine kinase | chr2:7515688-7516800 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • HSK (HOMOSERINE KINASE); homoserine kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: HSK, DMR1 | homoserine kinase | chr2:7508606-7509718 FORWARD LENGTH=370 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS=Arabidopsis thaliana GN=HSK PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    Biological Process: methionine biosynthetic process [TAS]
    response to bacterium [IGI]
    threonine biosynthetic process [TAS]
    response to fungus [IGI]
    Molecular Function: homoserine kinase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLCFQSPS KPISYFQPKS NPSPPLFAKV SVFRCRASVQ TLVAVEPEPV FVSVKTFAPA  60
   61 TVANLGPGFD FLGCAVDGLG DHVTLRVDPS VRAGEVSISE ITGTTTKLST NPLRNCAGIA 120
  121 AIATMKMLGI RSVGLSLDLH KGLPLGSGLG SSAASAAAAA VAVNEIFGRK LGSDQLVLAG 180
  181 LESEAKVSGY HADNIAPAIM GGFVLIRNYE PLDLKPLRFP SDKDLFFVLV SPDFEAPTKK 240
  241 MRAALPTEIP MVHHVWNSSQ AAALVAAVLE GDAVMLGKAL SSDKIVEPTR APLIPGMEAV 300
  301 KKAALEAGAF GCTISGAGPT AVAVIDSEEK GQVIGEKMVE AFWKVGHLKS VASVKKLDNV 360
  361 GARLVNSVSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..370] PSI-BLAST 37.39794 Homoserine kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0246382239358082 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle