YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HMGCL_ARATH

General Information:
Name(s) found: HMGCL_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
SHOW ALL
  • Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Arabidopsis thaliana GN=HMGCL PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    Biological Process: metabolic process [IEA]
    leucine metabolic process [ISS]
    Molecular Function: catalytic activity [IEA]
    hydroxymethylglutaryl-CoA lyase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQWNGVRRAH SIWCKRLTNN THLHHPSIPV SHFFTMSSLE EPLSFDKLPS MSTMDRIQRF  60
   61 SSGACRPRDD VGMGHRWIEG RDCTTSNSCI DDDKSFAKES FPWRRHTRKL SEGEHMFRNI 120
  121 SFAGRTSTVS GTLRESKSFK EQKYSTFSNE NGTSHISNKI SKGIPKFVKI VEVGPRDGLQ 180
  181 NEKNIVPTSV KVELIQRLVS SGLPVVEATS FVSPKWVPQL ADAKDVMDAV NTLDGARLPV 240
  241 LTPNLKGFQA AVSAGAKEVA IFASASESFS LSNINCTIEE SLLRYRVVAT AAKEHSVPVR 300
  301 GYVSCVVGCP VEGPVLPSKV AYVVKELYDM GCFEISLGDT IGIGTPGSVV PMLEAVMAVV 360
  361 PADKLAVHFH DTYGQALANI LVSLQMGISI VDSSIAGLGG CPYAKGASGN VATEDVVYML 420
  421 NGLGVHTNVD LGKLIAAGDF ISKHLGRPNG SKAAVALNRR ITADASKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] MSA 1.071981 View MSA. No confident structure predictions are available.
    2 View Details [160..468] PSI-BLAST 92.69897 Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle