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Protein Overview: SMC5_ARATH

General Information:
Name(s) found: SMC5_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Structural maintenance of chromosomes protein 5 OS=Arabidopsis thaliana GN=SMC5 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1053 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    chromosome [IEA]
    Biological Process: sister chromatid cohesion [IMP]
    chromosome segregation [ISS]
    Molecular Function: ATP binding [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERRAKRPK ISRGEDDFLP GNIIEIELHN FMTFNHLVCK PGSRLNLVIG PNGSGKSSLV  60
   61 CAIALCLGGE PQLLGRATSV GAYVKRGEDS GYVKISLRGN TREENLTIFR KIDTRNKSEW 120
  121 MFNGSTVSKK DIVEIIQKFN IQVNNLTQFL PQDRVCEFAK LTPVQLLEET EKAVGDPQLP 180
  181 VHHRALVEKS RDLKQLERAV AKNGETLNQL KALVDEQEKD VERVRQRELF LTKVDSMKKK 240
  241 LPWLKYDMKK AEYMDAKKRM KEAEKKLDEA AKNLNSMKEP IEKQKKEKAE TDSKCKKVKN 300
  301 LMDANGRNRC HLLEKEDEAD ARVVATYKEL EELKKQEEHR QERILKATED LVAAERELQN 360
  361 LPVYERPVAK LEELSSQVTE LHHSINGKKN QKEDNEKLLS QKRYTLRQCV DKLKDMENAN 420
  421 NKLLKALANS GADRIFDAYQ WVQQNRHEFK REVYGPVLVE VNVPNRENAC FLEGHVSFYI 480
  481 WKSFITQDPE DRDLLVKNLK RFDVPVLNYV GNSGNQKAPF HISDQMRSLG IHARLDQIFD 540
  541 APDAVKEVLN SQFGLEDSYI GSKITDQRAE EVYKLGIKDF WTPDNHYRWS SSRYGGHSSA 600
  601 SVDSVYQSRL LLCGVDVGEL EKLRSRKEEL EDSILFMEET HKSLQTEQRR LEEEAAKLHK 660
  661 EREEIVNVSY LEKKKRRELE SRYQQRKTKL ESLEQEEDMD ASVAKLIDQA SRANADRYTY 720
  721 AINLKKLLVE AVAHKWSYAE KHMASIELER KIRESEINIK QYEKTAQQLS LAVEYCKKEV 780
  781 EGKQQRLATA KRDAESVATI TPELKKEFME MPTTVEELEA AIQDNLSQAN SILFINENIL 840
  841 QEYEHRQSQI YTISTKLETD KRDLSICMKE IDSLKEKWLP TLRQLVGQIN ETFSHNFQEM 900
  901 AVAGEVSLDE RDTDFDQYGI HIKVKFRESG QLQVLSSHHQ SGGERSVSTI LYLVSLQDLT 960
  961 NCPFRVVDEI NQGMDPINER KMFQQLVRAA SQPNTPQCFL LTPKLLPELE YSEACSILNI1020
 1021 MNGPYIAEPS KVWSLGDSWG SLNRRRTEAS QCS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] PSI-BLAST 23.522879 Sc Smc1hd:Scc1-C complex, ATPgS
    2 View Details [146..480] PSI-BLAST 21.0 Heavy meromyosin subfragment
    3 View Details [481..555] deduced N/A No confident structure predictions are available.
    4 View Details [556..825] PSI-BLAST 3.09691 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
    5 View Details [826..883] PSI-BLAST 9.045757 Tropomyosin
    6 View Details [884..961] PSI-BLAST 9.045757 Tropomyosin
    7 View Details [962..1053] PSI-BLAST 21.30103 Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle