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Protein Overview: DNMT3_ARATH

General Information:
Name(s) found: DNMT3_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T06663 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) T6G15.160 - Arabidopsis thaliana [NCBI NR]
  • gi|7268065|emb|CAB78403.1| DNA (cytosine-5-)-methyltransferase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|4678387|emb|CAB41119.1| DNA (cytosine-5-)-methyltransferase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15236318|ref|NP_193097.1| MEE57 (maternal effect embryo arrest 57); DNA (cytosine-5-)-methyltransferase/ DNA binding / protein binding [Arabidopsis thaliana] [NCBI NR]
  • DNA (cytosine-5)-methyltransferase 3 OS=Arabidopsis thaliana GN=MET3 PE=3 SV=1 [Swiss-Prot]
  • (Q9T0I1) DNA (Cytosine-5-)-methyltransferase-like protein (EC 2.1.1.37) (Modification methylase) (Cytosine-specific methyltransferase) [athaliana3702.FASTAC.txt]
  • DNA (cytosine-5-)-methyltransferase-like protein [Arabidopsis thaliana]gi|7268065|emb|CAB78403.1| DNA (cytosine-5-)-methyltransferase-like protein [Arabidopsis thaliana]gi|7484923|pir||T06663 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) T6G15.160 - [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 DNA (cytosine-5-)-methyltransferase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: MEE57 | MEE57 (maternal effect embryo arrest 57); DNA (cytosine-5-)-methyltransferase | chr4:7915018-7921227 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA (cytosine-5-)-methyltransferase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • DNA (cytosine-5-)-methyltransferase/ DNA binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: MEE57 | DNA (cytosine-5-)-methyltransferase family protein | chr4:7915022-7921231 FORWARD LENGTH=1404 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Cytosine-specific methyltransferase OS=Arabidopsis thaliana GN=T6G15.160 PE=3 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1404 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: DNA methylation [ISS]
    embryonic development ending in seed dormancy [IMP]
    Molecular Function: DNA (cytosine-5-)-methyltransferase activity [IEA][ISS]
    DNA binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTKAGKQKK RSVDSDDDVS RERRPKRATS GTNFKEKSLR FSEKYETVEA KKEQIVGDDE  60
   61 KEEKGVRFQS FGRVENWTIS GYEDGSPVIW ISTVIADYDC RKPSKKYKKL YDYFFEKACA 120
  121 CVEVCKNLST NPDTSLKELL AAVVRSMNGR KIFSSGGVIQ EFVISQGEFI YNQLAGLDET 180
  181 SKNHETKFVD NRVLVSLRDE SRKIHKAFSN VALRIDESKV LTSDQLMDGG EDEDLKYAKL 240
  241 LQEEEHMKSM DRSRNKRSST TSAPNKFYIK INEDEIAHDY PLPSYYKNTK DETDELVLFN 300
  301 AGYAVDARNL PCRTLHNWAL YNSDLMLISL EFLPMKPCAD IDVTYLGQIK EWKIDFGEDM 360
  361 IFVLLRTDMA WYRLGKPSEQ YAPWFEPILK TVRIGTSILA LLKNETRMAK LSYTDVIKRL 420
  421 CGLEENDQAY ISSTFFDVER YVIVHGQIIL QFLTECPDEY IKRCPFVTGL ASKMQDRHHT 480
  481 KWIIKKKRKM LQKGENLNLR RGKAPKVSKM KAMQATTTRL INRIWGEFYS IYSPEDPLEE 540
  541 IGAEEEFEEV EDVEEEDENE EEDTIQKAIE VQKADTLKKI RGSCKEMEIR WEGEILGETC 600
  601 AGEPLYGQAL VGGRKMDVGG AVILEVDDQG ETPLIYFVEY MFESSDNSKK LHGKLLQRGS 660
  661 ETVLGTAANE RELFLTNECL TVQLKDIKGT VSFEIRSRPW GHQYKKEHMA ADKLDRARAE 720
  721 ERKAKDLPIE YYCKSLYSPE KGGFFSLPRS DMGLGSGFCS SCKIRENEEE RSKTKLNDSK 780
  781 TRFLSNGIKY SVGDFVYQIP NYLSKDRGKR RPVFKYGRNV GLRAFVVCQI LDIVDLKEPK 840
  841 KGNTTSFEVK VRRFYRPDDV SAEEAYASDI QEVYYSEDTY ILPPEAIKGK CEVMKKTDMP 900
  901 LCREYPILDH VYFCDRFYDS SNGCLKKLPY NMMLKFSTIK DDTLLREKKT ETGSAMLLKP 960
  961 DEVPKGKRLA TLDIFAGCGG LSYGLEKAGV SDTKWAIEYE EPAAQAFKQN HPKTTVFVDN1020
 1021 CNVILRISWL RLLINDRAIM EKCGDVDDCI STTEAAELAT KLDENQKSTL PLPGQVDFIS1080
 1081 GGPPCQGFSR LNRFSDGSWS KNQCQMILAF LSFADYFRPK YFLLENVKTF VSFNEGHTFH1140
 1141 LTVASLLEMG YQVRFGLLEA GAYGISQPRK RAFIWAAAPN EVLPEWPEPM HVFNNPGFKI1200
 1201 PLSQGLHYAA VQSTKFGAPF RSITVRDAIG DLPPIESGES KINKEEMRGS MTVLTDHICK1260
 1261 KMNELNLIRC KKIPKTPGAD WRDLPDEHVN LSNGIVKNIV PNLLNKAKDH NGYKGLYGRL1320
 1321 DWHGNLPTCI TNLQPMGLVG MCFHPDQDRI ISVRECARSQ GFPDSYKFSG NIKDKHRQVG1380
 1381 NAVPPPLAFA LGRKLKEALH LRNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] MSA 1.004975 View MSA. No confident structure predictions are available.
    2 View Details [185..258] deduced N/A No confident structure predictions are available.
    3 View Details [259..499] PSI-BLAST 3.69897 No description for 2grcA was found.
    4 View Details [500..590] deduced N/A No confident structure predictions are available.
    5 View Details [591..768] PSI-BLAST 36.39794 Crystal structure of the proximal BAH domain of polybromo
    6 View Details [769..956] MSA 3.16899 View MSA. No confident structure predictions are available.
    7 View Details [957..1404] PSI-BLAST 49.39794 DNA methylase HaeIII


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle