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View Structure Prediction Details

Protein: DNMT3_ARATH
Organism: Arabidopsis thaliana
Length: 1404 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for DNMT3_ARATH.

Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTKAGKQKK RSVDSDDDVS RERRPKRATS GTNFKEKSLR FSEKYETVEA KKEQIVGDDE  60
   61 KEEKGVRFQS FGRVENWTIS GYEDGSPVIW ISTVIADYDC RKPSKKYKKL YDYFFEKACA 120
  121 CVEVCKNLST NPDTSLKELL AAVVRSMNGR KIFSSGGVIQ EFVISQGEFI YNQLAGLDET 180
  181 SKNH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETKFVDNRVL VSLRDESRKI HKAFSNVALR IDESKVLTSD QLMDGGEDED LKYAKLLQEE  60
   61 EHMKSMDRSR NKRS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [259-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTSAPNKFY IKINEDEIAH DYPLPSYYKN TKDETDELVL FNAGYAVDAR NLPCRTLHNW  60
   61 ALYNSDLMLI SLEFLPMKPC ADIDVTYLGQ IKEWKIDFGE DMIFVLLRTD MAWYRLGKPS 120
  121 EQYAPWFEPI LKTVRIGTSI LALLKNETRM AKLSYTDVIK RLCGLEENDQ AYISSTFFDV 180
  181 ERYVIVHGQI ILQFLTECPD EYIKRCPFVT GLASKMQDRH HTKWIIKKKR KMLQKGENLN 240
  241 L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 2grcA
Description: No description for 2grcA was found.

Predicted Domain #4
Region A:
Residues: [500-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRGKAPKVSK MKAMQATTTR LINRIWGEFY SIYSPEDPLE EIGAEEEFEE VEDVEEEDEN  60
   61 EEEDTIQKAI EVQKADTLKK IRGSCKEMEI R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [591-768]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WEGEILGETC AGEPLYGQAL VGGRKMDVGG AVILEVDDQG ETPLIYFVEY MFESSDNSKK  60
   61 LHGKLLQRGS ETVLGTAANE RELFLTNECL TVQLKDIKGT VSFEIRSRPW GHQYKKEHMA 120
  121 ADKLDRARAE ERKAKDLPIE YYCKSLYSPE KGGFFSLPRS DMGLGSGFCS SCKIRENE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 1w4sA
Description: Crystal structure of the proximal BAH domain of polybromo
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [769-956]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EERSKTKLND SKTRFLSNGI KYSVGDFVYQ IPNYLSKDRG KRRPVFKYGR NVGLRAFVVC  60
   61 QILDIVDLKE PKKGNTTSFE VKVRRFYRPD DVSAEEAYAS DIQEVYYSED TYILPPEAIK 120
  121 GKCEVMKKTD MPLCREYPIL DHVYFCDRFY DSSNGCLKKL PYNMMLKFST IKDDTLLREK 180
  181 KTETGSAM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [957-1404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLKPDEVPKG KRLATLDIFA GCGGLSYGLE KAGVSDTKWA IEYEEPAAQA FKQNHPKTTV  60
   61 FVDNCNVILR ISWLRLLIND RAIMEKCGDV DDCISTTEAA ELATKLDENQ KSTLPLPGQV 120
  121 DFISGGPPCQ GFSRLNRFSD GSWSKNQCQM ILAFLSFADY FRPKYFLLEN VKTFVSFNEG 180
  181 HTFHLTVASL LEMGYQVRFG LLEAGAYGIS QPRKRAFIWA AAPNEVLPEW PEPMHVFNNP 240
  241 GFKIPLSQGL HYAAVQSTKF GAPFRSITVR DAIGDLPPIE SGESKINKEE MRGSMTVLTD 300
  301 HICKKMNELN LIRCKKIPKT PGADWRDLPD EHVNLSNGIV KNIVPNLLNK AKDHNGYKGL 360
  361 YGRLDWHGNL PTCITNLQPM GLVGMCFHPD QDRIISVREC ARSQGFPDSY KFSGNIKDKH 420
  421 RQVGNAVPPP LAFALGRKLK EALHLRNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.39794
Match: 1dctA
Description: DNA methylase HaeIII
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle