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Protein Overview: DNMT4_ARATH

General Information:
Name(s) found: DNMT4_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||G71402 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) DL3110W - Arabidopsis thaliana [NCBI NR]
  • gi|7268119|emb|CAB78456.1| (cytosine-5-)-methyltransferase [Arabidopsis thaliana] [NCBI NR]
  • gi|2244770|emb|CAB10193.1| (cytosine-5-)-methyltransferase [Arabidopsis thaliana] [NCBI NR]
  • gi|15236413|ref|NP_193150.1| DMT2 (DNA METHYLTRANSFERASE 2); DNA (cytosine-5-)-methyltransferase/ DNA binding / protein binding [Arabidopsis thaliana] [NCBI NR]
  • DNA (cytosine-5)-methyltransferase 4 OS=Arabidopsis thaliana GN=MET4 PE=2 SV=1 [Swiss-Prot]
  • (O23273) (Cytosine-5-)-methyltransferase (EC 2.1.1.73) (Modification methylase) (Cytosine-specific methyltransferase) [athaliana3702.FASTAC.txt]
  • (cytosine-5-)-methyltransferase [Arabidopsis thaliana]gi|2244770|emb|CAB10193.1| (cytosine-5-)-methyltransferase [Arabidopsis thaliana]gi|7484922|pir||G71402 DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37) DL3110W - Arabidopsis thalianagi|15236413|re [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 DNA (cytosine-5-)-methyltransferase (METII) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: MET2, DMT02, DMT2, MET02 | MET2 (DNA METHYLTRANSFERASE 2); DNA (cytosine-5-)-methyltransferase | chr4:8146340-8152126 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • MET2; DNA (cytosine-5-)-methyltransferase/ DNA binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • (cytosine-5-)-methyltransferase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: MET2, DMT02, DMT2, MET02 | DNA methyltransferase 2 | chr4:8146345-8152131 FORWARD LENGTH=1519 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Cytosine-specific methyltransferase OS=Arabidopsis thaliana GN=dl3110w PE=3 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1519 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: DNA mediated transformation [IMP]
    DNA methylation [ISS]
    Molecular Function: DNA (cytosine-5-)-methyltransferase activity [IEA][ISS]
    DNA binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMETKAGKQ KKRSVDSDDD VSKERRPKRA AACTNFKEKS LRISDKSETV EAKKEQILAE  60
   61 EIVAIQLTSS LESNDDPRPN RRLTDFVLHD SEGVPQPVEM LELGDIFIEG VVLPLGDEKK 120
  121 EEKGVRFQSF GRVENWNISG YEDGSPVIWI STALADYDCR KPSKKYKKLY DYFFEKACAC 180
  181 VEVFKSLSKN PDTSLDELLA AVSRSMSGSK IFSSGGAIQE FVISQGEFIY NQLAGLDETA 240
  241 KNHETCFVEN RVLVSLRDHE SNKIHKALSN VALRIDESKV VTSDHLVDGA EDEDVKYAKL 300
  301 IQEEEYRKSM ERSRNKRSST TSGGSSRFYI KISEDEIADD YPLPSYYKNT KEETDELVLF 360
  361 EAGYEVDTRD LPCRTLHNWT LYNSDSRMIS LEVLPMRPCA EIDVTVFGSG VVAEDDGSGF 420
  421 CLDDSESSTS TQSNDHDGMN IFLSQIKEWM IEFGAEMIFV TLRTDMAWYR LGKPSKQYAP 480
  481 WFGTVMKTVR VGISIFNMLM RESRVAKLSY ANVIKRLCGL EENDKAYISS KLLDVERYVV 540
  541 VHGQIILQLF EEYPDKDIKR CPFVTSLASK MQDIHHTKWI IKKKKKILQK GKNLNPRAGI 600
  601 APVVSRMKAM QATTTRLVNR IWGEFYSIYS PEVPSEAINA ENVEEEELEE VEEEDENEED 660
  661 DPEENELEAV EIQNSPTPKK IKGISEDMEI KWDGEILGKT SAGEPLYGRA FVGGDVVVVG 720
  721 SAVILEVDDQ DDTQLICFVE FMFESSNHSK MLHGKLLQRG SETVLGMAAN ERELFLTNEC 780
  781 LTVQLKDIKG TVSLEIRSRL WGHQYRKENI DVDKLDRARA EERKTNGLPT DYYCKSLYSP 840
  841 ERGGFFSLPR NDMGLGSGFC SSCKIRENEE ERSKTKLNDS KTGFLSNGIE YHNGDFVYVL 900
  901 PNYITKDGLK KGSRRTTLKC GRNVGLKAFV VCQLLDVIVL EESRKASKAS FQVKLTRFYR 960
  961 PEDISEEKAY ASDIQELYYS QDTYILPPEA IQGKCEVRKK SDMPLCREYP ILDHIFFCEV1020
 1021 FYDSSTGYLK QFPANMKLKF STIKDETLLR EKKGKGVETG TSSGMLMKPD EVPKEKPLAT1080
 1081 LDIFAGCGGL SHGLENAGVS TTKWAIEYEE PAGHAFKQNH PEATVFVDNC NVILRAIMEK1140
 1141 CGDVDDCVST VEAAELAAKL DENQKSTLPL PGQVDFINGG PPCQGFSGMN RFSHGSWSKV1200
 1201 QCEMILAFLS FADYFRPKYF LLENVKKFVT YNKGRTFQLT MASLLEMGYQ VRFGILEAGT1260
 1261 YGVSQPRKRV IIWAASPEEV LPEWPEPMHV FDNPGSKISL PRGLRYDAGC NTKFGAPFRS1320
 1321 ITVRDTIGDL PPVENGESKI NKEYGTTPAS WFQKKIRGNM SVLTDHICKG LNELNLIRCK1380
 1381 KIPKRPGADW RDLPDENVTL SNGLVEKLRP LALSKTAKNH NEWKGLYGRL DWQGNLPISI1440
 1441 TDPQPMGKVG MCFHPEQDRI ITVRECARSQ GFPDSYEFSG TTKHKHRQIG NAVPPPLAFA1500
 1501 LGRKLKEALY LKSSLQHQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] MSA 1.01297 View MSA. No confident structure predictions are available.
    2 View Details [153..216] deduced N/A No confident structure predictions are available.
    3 View Details [217..560] PSI-BLAST 11.0 No description for 2r0vA was found.
    4 View Details [561..686] PSI-BLAST 8.69897 TAFII250 double bromodomain module
    5 View Details [687..871] PSI-BLAST 34.69897 Crystal structure of the proximal BAH domain of polybromo
    6 View Details [872..965] deduced N/A No confident structure predictions are available.
    7 View Details [966..1074] MSA 2.223995 View MSA. No confident structure predictions are available.
    8 View Details [1075..1519] PSI-BLAST 39.154902 DNA methylase HaeIII


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle