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View Structure Prediction Details

Protein: DNMT4_ARATH
Organism: Arabidopsis thaliana
Length: 1519 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for DNMT4_ARATH.

Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMETKAGKQ KKRSVDSDDD VSKERRPKRA AACTNFKEKS LRISDKSETV EAKKEQILAE  60
   61 EIVAIQLTSS LESNDDPRPN RRLTDFVLHD SEGVPQPVEM LELGDIFIEG VVLPLGDEKK 120
  121 EEKGVRFQSF GRVENWNISG YEDGSPVIWI ST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALADYDCRKP SKKYKKLYDY FFEKACACVE VFKSLSKNPD TSLDELLAAV SRSMSGSKIF  60
   61 SSGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [217-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIQEFVISQG EFIYNQLAGL DETAKNHETC FVENRVLVSL RDHESNKIHK ALSNVALRID  60
   61 ESKVVTSDHL VDGAEDEDVK YAKLIQEEEY RKSMERSRNK RSSTTSGGSS RFYIKISEDE 120
  121 IADDYPLPSY YKNTKEETDE LVLFEAGYEV DTRDLPCRTL HNWTLYNSDS RMISLEVLPM 180
  181 RPCAEIDVTV FGSGVVAEDD GSGFCLDDSE SSTSTQSNDH DGMNIFLSQI KEWMIEFGAE 240
  241 MIFVTLRTDM AWYRLGKPSK QYAPWFGTVM KTVRVGISIF NMLMRESRVA KLSYANVIKR 300
  301 LCGLEENDKA YISSKLLDVE RYVVVHGQII LQLFEEYPDK DIKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 2r0vA
Description: No description for 2r0vA was found.

Predicted Domain #4
Region A:
Residues: [561-686]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPFVTSLASK MQDIHHTKWI IKKKKKILQK GKNLNPRAGI APVVSRMKAM QATTTRLVNR  60
   61 IWGEFYSIYS PEVPSEAINA ENVEEEELEE VEEEDENEED DPEENELEAV EIQNSPTPKK 120
  121 IKGISE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1eqfA
Description: TAFII250 double bromodomain module
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [687-871]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMEIKWDGEI LGKTSAGEPL YGRAFVGGDV VVVGSAVILE VDDQDDTQLI CFVEFMFESS  60
   61 NHSKMLHGKL LQRGSETVLG MAANERELFL TNECLTVQLK DIKGTVSLEI RSRLWGHQYR 120
  121 KENIDVDKLD RARAEERKTN GLPTDYYCKS LYSPERGGFF SLPRNDMGLG SGFCSSCKIR 180
  181 ENEEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1w4sA
Description: Crystal structure of the proximal BAH domain of polybromo
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [872-965]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSKTKLNDSK TGFLSNGIEY HNGDFVYVLP NYITKDGLKK GSRRTTLKCG RNVGLKAFVV  60
   61 CQLLDVIVLE ESRKASKASF QVKLTRFYRP EDIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [966-1074]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEKAYASDIQ ELYYSQDTYI LPPEAIQGKC EVRKKSDMPL CREYPILDHI FFCEVFYDSS  60
   61 TGYLKQFPAN MKLKFSTIKD ETLLREKKGK GVETGTSSGM LMKPDEVPK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1075-1519]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKPLATLDIF AGCGGLSHGL ENAGVSTTKW AIEYEEPAGH AFKQNHPEAT VFVDNCNVIL  60
   61 RAIMEKCGDV DDCVSTVEAA ELAAKLDENQ KSTLPLPGQV DFINGGPPCQ GFSGMNRFSH 120
  121 GSWSKVQCEM ILAFLSFADY FRPKYFLLEN VKKFVTYNKG RTFQLTMASL LEMGYQVRFG 180
  181 ILEAGTYGVS QPRKRVIIWA ASPEEVLPEW PEPMHVFDNP GSKISLPRGL RYDAGCNTKF 240
  241 GAPFRSITVR DTIGDLPPVE NGESKINKEY GTTPASWFQK KIRGNMSVLT DHICKGLNEL 300
  301 NLIRCKKIPK RPGADWRDLP DENVTLSNGL VEKLRPLALS KTAKNHNEWK GLYGRLDWQG 360
  361 NLPISITDPQ PMGKVGMCFH PEQDRIITVR ECARSQGFPD SYEFSGTTKH KHRQIGNAVP 420
  421 PPLAFALGRK LKEALYLKSS LQHQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.154902
Match: 1dctA
Description: DNA methylase HaeIII
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle