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Protein Overview: DPYD_ARATH

General Information:
Name(s) found: DPYD_ARATH [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic OS=Arabidopsis thaliana GN=PYD1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    plastid [IDA]
    Biological Process: 'de novo' pyrimidine base biosynthetic process [ISS]
    uracil catabolic process [IMP]
    cellular response to nitrogen levels [IEP]
    Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors [ISS]
    dihydropyrimidine dehydrogenase (NADP+) activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASMSFALNR FSGLSSKTTL SADFDPSSRR SFLPPTRVGL KISSAAESEP DLSVTVNGLK  60
   61 MPNPFVIGSG PPGTNYTVMK RAFDEGWGAV IAKTVSLDAS KVINVTPRYA RLRTGSNGSA 120
  121 KTDVIGWQNI ELISDRPLET MLKEFERLKK EYPDRILIAS VMEEYNKTAW EELIDRVEQT 180
  181 GVDALEINFS CPHGMPERRM GAAVGQDCAL LDEVCGWINA KATVPVWAKM TPNITDITEP 240
  241 ARVSLKSGCE GIAAINTIMS VMGIDMKTLR PEPCVEGYST PGGYSYKAVR PIALAKVMNI 300
  301 AKMMKSEFSE DRSLSGIGGV ETGYDAAEFI LLGSNTVQVC TGVMMHGYGH VKTLCAELKD 360
  361 FMKQHNFSTI EEFRGHSLQY FTTHTDLVKR QKEAVEQRKA EKRGLKSDKD WTGDGFVKET 420
  421 ESMVSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..426] PSI-BLAST 54.0 Dihydropyrimidine dehydrogenase, N-terminal domain; Dihydropyrimidine dehydrogenase, domain 4; Dihydropyrimidine dehydrogenase, domain 3; Dihydropyrimidine dehydrogenase, domain 2; Dihydropyrimidine dehydrogenase, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • dihydroorotate dehydrogenase activity
    		•  2.73800716363956 bayes_pls_golite062009
  • dihydroorotate oxidase activity
    		•  2.35584458985229 bayes_pls_golite062009
  • catalytic activity
    		•  1.94749091175302 bayes_pls_golite062009
  • dihydropyrimidine dehydrogenase (NADP+) activity
    		•  1.76080169529176 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.34004057547793 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  0.708198550325532 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle