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Protein Overview: GMAN2_ARATH

General Information:
Name(s) found: GMAN2_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Alpha-mannosidase 2 OS=Arabidopsis thaliana GN=GMII PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1173 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDA]
    Biological Process: protein amino acid N-linked glycosylation [IDA]
    Molecular Function: alpha-mannosidase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFSSYIGNS RRSSTGGGTG GWGQSLLPTA LSKSKLAINR KPRKRTLVVN FIFANFFVIA  60
   61 LTVSLLFFLL TLFHFGVPGP ISSRFLTSRS NRIVKPRKNI NRRPLNDSNS GAVVDITTKD 120
  121 LYDRIEFLDT DGGPWKQGWR VTYKDDEWEK EKLKIFVVPH SHNDPGWKLT VEEYYQRQSR 180
  181 HILDTIVETL SKDSRRKFIW EEMSYLERWW RDASPNKQEA LTKLVKDGQL EIVGGGWVMN 240
  241 DEANSHYFAI IEQIAEGNMW LNDTIGVIPK NSWAIDPFGY SSTMAYLLRR MGFENMLIQR 300
  301 THYELKKDLA QHKNLEYIWR QSWDAMETTD IFVHMMPFYS YDIPHTCGPE PAICCQFDFA 360
  361 RMRGFKYELC PWGKHPVETT LENVQERALK LLDQYRKKST LYRTNTLLIP LGDDFRYISI 420
  421 DEAEAQFRNY QMLFDHINSN PSLNAEAKFG TLEDYFRTVR EEADRVNYSR PGEVGSGQVV 480
  481 GFPSLSGDFF TYADRQQDYW SGYYVSRPFF KAVDRVLEHT LRGAEIMMSF LLGYCHRIQC 540
  541 EKFPTSFTYK LTAARRNLAL FQHHDGVTGT AKDYVVQDYG TRMHTSLQDL QIFMSKAIEV 600
  601 LLGIRHEKEK SDQSPSFFEA EQMRSKYDAR PVHKPIAARE GNSHTVILFN PSEQTREEVV 660
  661 TVVVNRAEIS VLDSNWTCVP SQISPEVQHD DTKLFTGRHR LYWKASIPAL GLRTYFIANG 720
  721 NVECEKATPS KLKYASEFDP FPCPPPYSCS KLDNDVTEIR NEHQTLVFDV KNGSLRKIVH 780
  781 RNGSETVVGE EIGMYSSPES GAYLFKPDGE AQPIVQPDGH VVTSEGLLVQ EVFSYPKTKW 840
  841 EKSPLSQKTR LYTGGNTLQD QVVEIEYHVE LLGNDFDDRE LIVRYKTDVD NKKVFYSDLN 900
  901 GFQMSRRETY DKIPLQGNYY PMPSLAFIQG SNGQRFSVHS RQSLGVASLK EGWLEIMLDR 960
  961 RLVRDDGRGL GQGVMDNRAM TVVFHLLAES NISQADPASN TNPRNPSLLS HLIGAHLNYP1020
 1021 INTFIAKKPQ DISVRVPQYG SFAPLAKPLP CDLHIVNFKV PRPSKYSQQL EEDKPRFALI1080
 1081 LNRRAWDSAY CHKGRQVNCT SMANEPVNFS DMFKDLAASK VKPTSLNLLQ EDMEILGYDD1140
 1141 QELPRDSSQP REGRVSISPM EIRAYKLELR PHK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] deduced N/A No confident structure predictions are available.
    2 View Details [87..1173] PSI-BLAST 1000.0 Golgi alpha-mannosidase II in complex with kifunensine

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • mannosidase activity
    		•  6.01915916767417 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.31715812247646 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.59000499388951 bayes_pls_golite062009
  • hydrolase activity
    		•  3.47408297144232 bayes_pls_golite062009
  • alpha-mannosidase activity
    		•  3.43578718881717 bayes_pls_golite062009
  • mannosyl-oligosaccharide mannosidase activity
    		•  2.67474348614438 bayes_pls_golite062009
  • deacetylase activity
    		•  2.13686837707321 bayes_pls_golite062009
  • binding
    		•  1.29644842078336 bayes_pls_golite062009
  • catalytic activity
    		•  1.17882014774774 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  1.00994109266252 bayes_pls_golite062009
  • racemase and epimerase activity, acting on carbohydrates and derivatives
    		•  0.68102716507433 bayes_pls_golite062009
  • aldose 1-epimerase activity
    		•  0.521235680233587 bayes_pls_golite062009
  • mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
    		•  0.511393435253234 bayes_pls_golite062009
  • racemase and epimerase activity
    		•  0.473636146090495 bayes_pls_golite062009
  • protein binding
    		•  0.394432087623352 bayes_pls_golite062009
  • isomerase activity
    		•  0.106573908779409 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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