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Protein Overview: LIAS_ARATH

General Information:
Name(s) found: LIAS_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|4454462|gb|AAD20909.1| lipoic acid synthase (LIP1) [Arabidopsis thaliana] [NCBI NR]
  • gi|3928758|dbj|BAA34701.1| Lipoic acid synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|16323378|gb|AAL15183.1| putative lipoic acid synthase LIP1 [Arabidopsis thaliana] [NCBI NR]
  • gi|15983418|gb|AAL11577.1|AF424583_1 At2g20860/F5H14.17 [Arabidopsis thaliana] [NCBI NR]
  • gi|15226412|ref|NP_179682.1| LIP1 (LIPOIC ACID SYNTHASE 1); lipoic acid synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|14334940|gb|AAK59647.1| putative lipoic acid synthase LIP1 [Arabidopsis thaliana] [NCBI NR]
  • pir||T44259 lipoic acid synthase (EC 2.8.1.-) [imported] - Arabidopsis thaliana [NCBI NR]
  • Lipoyl synthase, mitochondrial OS=Arabidopsis thaliana GN=LIP1 PE=2 SV=1 [Swiss-Prot]
  • (Q9ZWT1) Lipoic acid synthase (Putative lipoic acid synthase LIP1) (AT2G20860/F5H14.17) [athaliana3702.FASTAC.txt]
  • putative lipoic acid synthase LIP1 [Arabidopsis thaliana]gi|14334940|gb|AAK59647.1| putative lipoic acid synthase LIP1 [Arabidopsis thaliana]gi|4454462|gb|AAD20909.1| lipoic acid synthase (LIP1) [Arabidopsis thaliana]gi|15983418|gb|AAL11577.1| At2g2086 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Lipoic acid synthase (LIP1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: LIP1 | LIP1 (LIPOIC ACID SYNTHASE 1); lipoic acid synthase | chr2:8986717-8988064 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative lipoic acid synthase LIP1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At2g20860/F5H14.17 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • LIP1; lipoic acid synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Lipoic acid synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • lipoic acid synthase (LIP1) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: LIP1 | lipoic acid synthase 1 | chr2:8979636-8980983 FORWARD LENGTH=374 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 374 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IEP]
    mitochondrion [IEP]
    Biological Process: lipoic acid biosynthetic process [TAS]
    glycine catabolic process [TAS]
    Molecular Function: lipoic acid synthase activity [IGI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSRSALLYR FLRPASRCFS SSSAVTPVTV TQSPKSLEAL RARLANESPS LTDFIHGDTY  60
   61 SVEVGTKKKP LPKPKWMKES IPGGERYVQI KKKLRDLKLH TVCEEAKCPN LGECWSGGET 120
  121 GTATATIMIL GDTCTRGCRF CNVKTSRTPP PPDPNEPNNV AEAIASWGVD YVVITSVDRD 180
  181 DLPDQGSGHF AETVQRLKFL KPEMLIEALV PDFRGDGGCV EKVSKSGLDV LAHNIETVEE 240
  241 LQSFVRDHRA NFKQSLDVLR MAKEYAPAGT LTKTSVMLGC GETPDQVVKT MEKVRAAGVD 300
  301 VMTFGQYMRP SKRHMPVAEY VTPDAFERYR LLGMEMGFRY VASGPMVRSS YKAGEYYIKS 360
  361 MIEADRVASP STSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 63.522879 The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • sulfurtransferase activity
    		•  2.16438226990481 bayes_pls_golite062009
  • biotin synthase activity
    		•  2.08611410724267 bayes_pls_golite062009
  • coproporphyrinogen oxidase activity
    		•  1.98937742831419 bayes_pls_golite062009
  • radical SAM enzyme activity
    		•  1.93582371651697 bayes_pls_golite062009
  • catalytic activity
    		•  1.48331922124015 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  1.37188743230327 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.13381681474815 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.593156857804038 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.48341859452689 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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