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View Structure Prediction Details

Protein: LIAS_ARATH
Organism: Arabidopsis thaliana
Length: 374 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIAS_ARATH.

Description E-value Query
Range
Subject
Range
LIAS_BOVIN - Lipoyl synthase, mitochondrial OS=Bos taurus GN=LIAS PE=2 SV=1
332.0 [0..15] [369..2]

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Predicted Domain #1
Region A:
Residues: [1-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSRSALLYR FLRPASRCFS SSSAVTPVTV TQSPKSLEAL RARLANESPS LTDFIHGDTY  60
   61 SVEVGTKKKP LPKPKWMKES IPGGERYVQI KKKLRDLKLH TVCEEAKCPN LGECWSGGET 120
  121 GTATATIMIL GDTCTRGCRF CNVKTSRTPP PPDPNEPNNV AEAIASWGVD YVVITSVDRD 180
  181 DLPDQGSGHF AETVQRLKFL KPEMLIEALV PDFRGDGGCV EKVSKSGLDV LAHNIETVEE 240
  241 LQSFVRDHRA NFKQSLDVLR MAKEYAPAGT LTKTSVMLGC GETPDQVVKT MEKVRAAGVD 300
  301 VMTFGQYMRP SKRHMPVAEY VTPDAFERYR LLGMEMGFRY VASGPMVRSS YKAGEYYIKS 360
  361 MIEADRVASP STSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.522879
Match: 1r30A
Description: The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sulfurtransferase activity 2.16438226990481 bayes_pls_golite062009
biotin synthase activity 2.08611410724267 bayes_pls_golite062009
coproporphyrinogen oxidase activity 1.98937742831419 bayes_pls_golite062009
radical SAM enzyme activity 1.93582371651697 bayes_pls_golite062009
catalytic activity 1.48331922124015 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1.37188743230327 bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups 1.13381681474815 bayes_pls_golite062009
oxidoreductase activity 0.593156857804038 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.48341859452689 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle