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Protein Overview: P4KA2_ARATH

General Information:
Name(s) found: P4KA2_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Phosphatidylinositol 4-kinase alpha 2 OS=Arabidopsis thaliana GN=PI4KA2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: signal transduction [ISS]
    phosphoinositide biosynthetic process [ISS]
    Molecular Function: phosphoinositide binding [ISS]
    1-phosphatidylinositol 4-kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERLNELCDI IEQNPKQFLD KLPWICQQCP QSKLLRAESP RFSQSHLNAI LAVTRILSKI  60
   61 VDTTDENAKF VVLDFLQTVP KSFHRSFWPY SLSLESISAF YCSFLGYVSC LSQLMVEGYL 120
  121 LRAAQRSDIF AHTLIWHLQG ESVEEIVKDG AFDKNASFQE ILSDVRQHIV DGFTPKALNF 180
  181 FSREFDFFEK VTSISGALLP LPKEERVAGI RRELEKIKMQ GEDLYLPTAP NKLVRVIQVD 240
  241 SGIPLQSAAK VPIMITFNVV DLDGDHNDVK PQACIFKVGD DCRQDVLALQ VISLLGDIFQ 300
  301 AVGLNLYLFP YGVLPTVVPN TRSRSQMGET TDGGLYEIFQ QNYGLVGSTT FETARANFLI 360
  361 SSAGYAVASL LLQPKDRHNG NLLFDDVGRL VHIDFGFILE TSPGGNMRFE NAHFKLSHEM 420
  421 TQLLDPSGVM KSKTWHQFVS LCVKGYLAAR RYMDEIISTV QMMLESGLPC FSRGDPIGNL 480
  481 RKRFHPEMSE REAALFMINV CTDAYNKWTT AGYDLIQYLQ QGVEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..525] PSI-BLAST 124.0 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.06347528042278 bayes_pls_golite062009
  • kinase activity
    		•  1.02409755159573 bayes_pls_golite062009
  • binding
    		•  0.965705916566869 bayes_pls_golite062009
  • protein kinase activity
    		•  0.933596056888996 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.904491209582148 bayes_pls_golite062009
  • transferase activity
    		•  0.467738620631271 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.453529572806301 bayes_pls_golite062009
  • catalytic activity
    		•  0.316052266554946 bayes_pls_golite062009
  • protein binding
    		•  0.113616704254907 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0300488593105301 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle