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Protein Overview: SMC6A_ARATH

General Information:
Name(s) found: SMC6A_ARATH [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • Structural maintenance of chromosomes protein 6A OS=Arabidopsis thaliana GN=SMC6A PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1058 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    membrane [IEA]
    chromosome [IEA]
    Biological Process: sister chromatid cohesion [IMP]
    response to X-ray [IMP]
    double-strand break repair via homologous recombination [IMP]
    chromosome segregation [ISS]
    Molecular Function: two-component sensor activity [IEA]
    ATP binding [IEA][ISS]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEHGDHRQS NPFNDQQTSS GKILRIRLEN FMCHSNLEIE FGDWVNFITG QNGSGKSAIL  60
   61 TALCVAFGCR ARGTQRAATL KDFIKTGCSY ALVYVELKNQ GEDAFKPEIY GDTLIIERRI 120
  121 SDSTSLTVLK DHQGRKISSR KEELRELVEH YNIDVENPCV IMSQDKSREF LHSGNDKDKF 180
  181 KFFYKATLLQ QVDDILQSIG TKLNSANALL DEMEKTIKPI EKEINELLEK IKNMEHVEEI 240
  241 TQQVLHLKKK LAWSWVYDVD RQLKEQNEKI VKFKERVPTC QNKIDRKLGE VESLRVSLTE 300
  301 KKAQVACLID ESTAMKRELE CLRQSMKKAA REKIALEEEY HHKCSNIQKI KDRVRRLERQ 360
  361 IEDINEMTIR STQVEQSEIE GKLNQLTVEV EKAESLVSSL KEEENMVMEK ASAGGKEKEH 420
  421 IEEMIRDHEK KQRNMNAHIN DLKKHQTNKV TAFGGDKVIN LLRAIERHHR RFKMPPIGPI 480
  481 GAHVTLINGN RWASAVEQAL GNLLNAFIVT DHKDLVALRD CGKEAKYNNL KIIIYDFSRP 540
  541 RLDIPRHMIP QTEHPTILSV LHSENTTVLN VLVDVSCVER HVLAENYEVG KIIAFERRLS 600
  601 HLKDVFTIDG YRMFSRGPVQ TTLPPRPRRP TRLCASFDDQ IKDLEIEASR EQSEIQECRG 660
  661 QKREAEMNLE GLESTMRRLK KQRTQLEKDL TRKELEMQDL KNSVASETKA SPTSSVNELH 720
  721 LEIMKFQKEI EEKESLLEKL QDSLKEAELK ANELKASYEN LYESAKGEIE ALEKAEDELK 780
  781 EKEDELHSAE TEKNHYEDIM KDKVLPEIKQ AETIYKELEM KRQESNKKAS IICPESEIKA 840
  841 LGPWDGPTPL QLSAQINKIN HRLKRENENY SESIDDLRIM HGEKEQKIGK KRKTYKSCRE 900
  901 KLKVCKDAVD SRWNKLQRNK DLLKRELTWQ FNHHLGKKGI SGNIRVSYED KTLSIEVKMP 960
  961 QDATNSAVRD TRGLSGGERS FSTLCFTLAL QNMTEAPIRA MDEFDVFMDA VSRKISLDTL1020
 1021 IDFALKQGSQ WMFITPHDIS MVKSHEKIKK QQMAAPRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 35.522879 Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
    2 View Details [135..433] PSI-BLAST 19.09691 Heavy meromyosin subfragment
    3 View Details [434..528] deduced N/A No confident structure predictions are available.
    4 View Details [529..885] PSI-BLAST 10.09691 Tropomyosin
    5 View Details [886..1058] PSI-BLAST 22.30103 Sc Smc1hd:Scc1-C complex, ATPgS


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle