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Protein Overview: MTNA_ARATH

General Information:
Name(s) found: MTNA_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|20197503|gb|AAC95160.2| putative translation initiation factor eIF-2B alpha subunit [Arabidopsis thaliana] [NCBI NR]
  • gi|18396170|ref|NP_027726.1| eukaryotic translation initiation factor 2B family protein / eIF-2B family protein [Arabidopsis thaliana] [NCBI NR]
  • Methylthioribose-1-phosphate isomerase OS=Arabidopsis thaliana GN=At2g05830 PE=1 SV=2 [Swiss-Prot]
  • (Q9ZUG4) Putative translation initiation factor eIF-2B alpha subunit [athaliana3702.FASTAC.txt]
  • putative translation initiation factor eIF-2B alpha subunit [Arabidopsis thaliana]gi|18396170|ref|NP_027726.1| eukaryotic translation initiation factor 2B family protein / eIF-2B family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Eukaryotic translation initiation factor 2B family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | eukaryotic translation initiation factor 2B family protein / eIF-2B family protein | chr2:2229756-2231836 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative translation initiation factor eIF-2B alpha subunit [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • GTP binding / translation initiation factor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: | NagB/RpiA/CoA transferase-like superfamily protein | chr2:2229759-2231839 FORWARD LENGTH=374 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Methylthioribose-1-phosphate isomerase OS=Arabidopsis thaliana GN=At2g05830 PE=2 SV=2 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 374 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    eukaryotic translation initiation factor 2B complex [ISS]
    Biological Process: translational initiation [ISS]
    cellular biosynthetic process [IEA]
    cellular metabolic process [IEA]
    Molecular Function: GTP binding [ISS]
    translation initiation factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGEGDTTLK AICYKPGSLQ LLDQRKLPLE TIYLEIRDAS DGWSAIQEMV VRGAPAIAIA  60
   61 AALSLAVEVF NFHGFDGSAS DAVAFLENKL DYLVSSRPTA VNLADAALKL KHVIAKALAT 120
  121 ATEAKSIFKA YIEASEDMLE DDVVSNKAIG NFGLSLLRQQ AKNPDKLSVL THCNTGSLAT 180
  181 AGYGTALGVI RALHTQGILE RAYCTETRPF NQGSRLTAFE LVHEKIPATL IADSAAAALM 240
  241 KDGRVDGVIV GADRVASNGD TANKIGTYSL ALCAKHHGIP FYVAAPLTSV DLSLSSGKEI 300
  301 VIEERSPKEL MHTHGGLGER IAAPGISVWN PAFDMTPAEL IAGIITEKGV ITKNGNDTFD 360
  361 ISSFAKKITG NSSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 113.0 X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.56128901279222 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.40526340076289 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.987801998446038 bayes_pls_golite062009
  • binding
    		•  0.946249883212717 bayes_pls_golite062009
  • DNA binding
    		•  0.730721872216867 bayes_pls_golite062009
  • deaminase activity
    		•  0.518630450774121 bayes_pls_golite062009
  • S-methyl-5-thioribose-1-phosphate isomerase activity
    		•  0.511292518421556 bayes_pls_golite062009
  • transcription factor activity
    		•  0.195177143221873 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle