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Protein Overview: REF6_ARATH

General Information:
Name(s) found: REF6_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Lysine-specific demethylase REF6 OS=Arabidopsis thaliana GN=REF6 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1360 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: negative regulation of histone acetylation [IMP]
    unidimensional cell growth [IMP]
    leaf development [IMP]
    histone H3-K9 demethylation [IMP]
    vegetative to reproductive phase transition of meristem [IMP]
    response to brassinosteroid stimulus [IMP]
    Molecular Function: nucleic acid binding [IEA]
    transcription factor activity [ISS]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVSEQSQDV FPWLKSLPVA PEFRPTLAEF QDPIAYILKI EEEASRYGIC KILPPLPPPS  60
   61 KKTSISNLNR SLAARAAARV RDGGFGACDY DGGPTFATRQ QQIGFCPRKQ RPVQRPVWQS 120
  121 GEEYSFGEFE FKAKNFEKNY LKKCGKKSQL SALEIETLYW RATVDKPFSV EYANDMPGSA 180
  181 FIPLSLAAAR RRESGGEGGT VGETAWNMRA MSRAEGSLLK FMKEEIPGVT SPMVYVAMMF 240
  241 SWFAWHVEDH DLHSLNYLHM GAGKTWYGVP KDAALAFEEV VRVHGYGEEL NPLVTFSTLG 300
  301 EKTTVMSPEV FVKAGIPCCR LVQNPGEFVV TFPGAYHSGF SHGFNFGEAS NIATPEWLRM 360
  361 AKDAAIRRAA INYPPMVSHL QLLYDFVLAL GSRVPTSINP KPRSSRLKDK ARSEGERLTK 420
  421 KLFVQNIIHN NELLSSLGKG SPVALLPQSS SDISVCSDLR IGSHLITNQE NPIQLKCEDL 480
  481 SSDSVVVDLS NGLKDTVSVK EKFTSLCERS RNHLASTEKD TQETLSDAER RKNDAAVALS 540
  541 DQRLFSCVTC GVLSFDCVAI VQPKEAAARY LMSADCSFFN DWTAASGSAN LGQAARSLHP 600
  601 QSKEKHDVNY FYNVPVQTMD HSVKTGDQKT STTSPTIAHK DNDVLGMLAS AYGDSSDSEE 660
  661 EDQKGLVTPS SKGETKTYDQ EGSDGHEEAR DGRTSDFNCQ RLTSEQNGLS KGGKSSLLEI 720
  721 ALPFIPRSDD DSCRLHVFCL EHAAEVEQQL RPFGGINLML LCHPEYPRIE AEAKIVAEEL 780
  781 VINHEWNDTE FRNVTREDEE TIQAALDNVE AKGGNSDWTV KLGVNLSYSA ILSRSPLYSK 840
  841 QMPYNSIIYK AFGRSSPVAS SPSKPKVSGK RSSRQRKYVV GKWCGKVWMS HQVHPFLLEQ 900
  901 DLEGEESERS CHLRVAMDED ATGKRSFPNN VSRDSTTMFG RKYCRKRKIR AKAVPRKKLT 960
  961 SFKREDGVSD DTSEDHSYKQ QWRASGNEEE SYFETGNTAS GDSSNQMSDP HKGIIRHKGY1020
 1021 KEFESDDEVS DRSLGEEYTV RACAASESSM ENGSQHSMYD HDDDDDDIDR QPRGIPRSQQ1080
 1081 TRVFRNPVSY ESEDNGVYQQ SGRISISNRQ ANRMVGEYDS AENSLEERGF CSTGKRQTRS1140
 1141 TAKRIAKTKT VQSSRDTKGR FLQEFASGKK NEELDSYMEG PSTRLRVRHQ KPSRGSLETK1200
 1201 PKKIGKKRSG NASFSRVATE KDVEEKEEEE EEEENEEEEC AAYQCNMEGC TMSFSSEKQL1260
 1261 MLHKRNICPI KGCGKNFFSH KYLVQHQRVH SDDRPLKCPW KGCKMTFKWA WSRTEHIRVH1320
 1321 TGARPYVCAE PDCGQTFRFV SDFSRHKRKT GHSVKKTNKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..373] PSI-BLAST 87.0 No description for 2oq6A was found.
    2 View Details [374..600] deduced N/A No confident structure predictions are available.
    3 View Details [601..780] deduced N/A No confident structure predictions are available.
    4 View Details [781..1020] PSI-BLAST 54.09691 No description for 2i13A was found.
    5 View Details [1021..1135] PSI-BLAST 20.154902 Five-finger GLI1
    6 View Details [1136..1240] MSA 1.535996 View MSA. No confident structure predictions are available.
    7 View Details [1241..1360] PSI-BLAST 23.39794 Ying-yang 1 (yy1, zinc finger domain)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle