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Protein Overview: CMT1_ARATH

General Information:
Name(s) found: CMT1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|6503286|gb|AAF14662.1|AC011713_10 Identical to gb|AF039367 ecotype Col-0 chromomethylase (CMT1) gene from Arabidopsis thaliana [NCBI NR]
  • gi|2865416|gb|AAC02660.1| chromomethylase [Arabidopsis thaliana] [NCBI NR]
  • pir||H96839 hypothetical protein F23A5.9 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|18412893|ref|NP_565245.1| CMT1 (CHROMOMETHYLASE 1); DNA binding / chromatin binding [Arabidopsis thaliana] [NCBI NR]
  • gi|110832797|sp|O49139.2|CMT1_ARATH RecName: Full=Putative DNA (cytosine-5)-methyltransferase CMT1; AltName: Full=Chromomethylase 1; AltName: Full=Protein CHROMOMETHYLASE 1 [NCBI NR]
  • Putative DNA (cytosine-5)-methyltransferase CMT1 OS=Arabidopsis thaliana GN=CMT1 PE=5 SV=2 [Swiss-Prot]
  • (O49137) Chromomethylase (EC 2.1.1.73) (Modification methylase) (Cytosine-specific methyltransferase) [athaliana3702.FASTAC.txt]
  • Identical to gb|AF039367 ecotype Col-0 chromomethylase (CMT1) gene from Arabidopsis thalianagi|2865416|gb|AAC02660.1| chromomethylase [Arabidopsis thaliana]gi|25406689|pir||H96839 hypothetical protein F23A5.9 [imported] - Arabidopsis thalianagi|1841289 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Chromomethylase 1 (CMT1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: DMT4, CMT1 | CMT1 (CHROMOMETHYLASE 1); DNA binding | chr1:30347286-30351723 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • chromomethylase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Identical to gb|AF039367 ecotype Col-0 chromomethylase (CMT1) gene from Arabidopsis thaliana [nr-271106-contam.fasta]
  • DNA (cytosine-5)-methyltransferase CMT1 (Chromomethylase 1) (Protein CHROMOMETHYLASE1) [nr-271106-contam.fasta]
  • CMT1 (CHROMOMETHYLASE 1); DNA binding / chromatin binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: CMT1, DMT4 | chromomethylase 1 | chr1:30342394-30346831 FORWARD LENGTH=791 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 791 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    chromatin [IEA]
    Biological Process: DNA mediated transformation [IMP]
    DNA methylation [ISS]
    Molecular Function: DNA binding [IEA][ISS]
    chromatin binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARNKQKKR AEPESDLCFA GKPMSVVEST IRWPHRYQSK KTKLQAPTKK PANKGGKKED  60
   61 EEIIKQAKCH FDKALVDGVL INLNDDVYVT GLPGKLKFIA KVIELFEADD GVPYCRFRWY 120
  121 YRPEDTLIER FSHLVQPKRV FLSNDENDNP LTCIWSKVNI AKVPLPKITS RIEQRVIPPC 180
  181 DYYYDMKYEV PYLNFTSADD GSDASSSLSS DSALNCFENL HKDEKFLLDL YSGCGAMSTG 240
  241 FCMGASISGV KLITKWSVDI NKFACDSLKL NHPETEVRNE AAEDFLALLK EWKRLCEKFS 300
  301 LVSSTEPVES ISELEDEEVE ENDDIDEAST GAELEPGEFE VEKFLGIMFG DPQGTGEKTL 360
  361 QLMVRWKGYN SSYDTWEPYS GLGNCKEKLK EYVIDGFKSH LLPLPGTVYT VCGGPPCQGI 420
  421 SGYNRYRNNE APLEDQKNQQ LLVFLDIIDF LKPNYVLMEN VVDLLRFSKG FLARHAVASF 480
  481 VAMNYQTRLG MMAAGSYGLP QLRNRVFLWA AQPSEKLPPY PLPTHEVAKK FNTPKEFKDL 540
  541 QVGRIQMEFL KLDNALTLAD AISDLPPVTN YVANDVMDYN DAAPKTEFEN FISLKRSETL 600
  601 LPAFGGDPTR RLFDHQPLVL GDDDLERVSY IPKQKGANYR DMPGVLVHNN KAEINPRFRA 660
  661 KLKSGKNVVP AYAISFIKGK SKKPFGRLWG DEIVNTVVTR AEPHNQCVIH PMQNRVLSVR 720
  721 ENARLQGFPD CYKLCGTIKE KYIQVGNAVA VPVGVALGYA FGMASQGLTD DEPVIKLPFK 780
  781 YPECMQAKDQ I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..59] MSA 1.105996 View MSA. No confident structure predictions are available.
    2 View Details [60..207] PSI-BLAST 28.39794 Crystal structure of the proximal BAH domain of polybromo
    3 View Details [208..353] FFAS03 4.99 DNA methylase HaeIII
    4 View Details [354..791] PSI-BLAST 42.0 DNMT2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • DNA-methyltransferase activity
    		•  3.31632172292823 bayes_pls_golite062009
  • transferase activity
    		•  2.42370637689376 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.24556320310886 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.1789895493932 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  2.17404404470337 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.06810685308813 bayes_pls_golite062009
  • catalytic activity
    		•  1.62377578202456 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  1.36067005317038 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  0.740099749645209 bayes_pls_golite062009
  • DNA (cytosine-5-)-methyltransferase activity
    		•  0.6110460718981 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.49575399394607 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  0.0680860762896796 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle