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View Structure Prediction Details

Protein: CMT1_ARATH
Organism: Arabidopsis thaliana
Length: 791 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CMT1_ARATH.

Description E-value Query
Range
Subject
Range
gi|2865422 - gi|2865422|gb|AAC02663.1| chromomethylase [Arabidopsis thaliana]
584.0 [0..1] [791..1]

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Predicted Domain #1
Region A:
Residues: [1-59]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARNKQKKR AEPESDLCFA GKPMSVVEST IRWPHRYQSK KTKLQAPTKK PANKGGKKE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [60-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEEIIKQAKC HFDKALVDGV LINLNDDVYV TGLPGKLKFI AKVIELFEAD DGVPYCRFRW  60
   61 YYRPEDTLIE RFSHLVQPKR VFLSNDENDN PLTCIWSKVN IAKVPLPKIT SRIEQRVIPP 120
  121 CDYYYDMKYE VPYLNFTSAD DGSDASSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.39794
Match: 1w4sA
Description: Crystal structure of the proximal BAH domain of polybromo
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [208-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSSDSALNCF ENLHKDEKFL LDLYSGCGAM STGFCMGASI SGVKLITKWS VDINKFACDS  60
   61 LKLNHPETEV RNEAAEDFLA LLKEWKRLCE KFSLVSSTEP VESISELEDE EVEENDDIDE 120
  121 ASTGAELEPG EFEVEKFLGI MFGDPQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.99
Match: 1dctA
Description: DNA methylase HaeIII
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [354-791]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTGEKTLQLM VRWKGYNSSY DTWEPYSGLG NCKEKLKEYV IDGFKSHLLP LPGTVYTVCG  60
   61 GPPCQGISGY NRYRNNEAPL EDQKNQQLLV FLDIIDFLKP NYVLMENVVD LLRFSKGFLA 120
  121 RHAVASFVAM NYQTRLGMMA AGSYGLPQLR NRVFLWAAQP SEKLPPYPLP THEVAKKFNT 180
  181 PKEFKDLQVG RIQMEFLKLD NALTLADAIS DLPPVTNYVA NDVMDYNDAA PKTEFENFIS 240
  241 LKRSETLLPA FGGDPTRRLF DHQPLVLGDD DLERVSYIPK QKGANYRDMP GVLVHNNKAE 300
  301 INPRFRAKLK SGKNVVPAYA ISFIKGKSKK PFGRLWGDEI VNTVVTRAEP HNQCVIHPMQ 360
  361 NRVLSVRENA RLQGFPDCYK LCGTIKEKYI QVGNAVAVPV GVALGYAFGM ASQGLTDDEP 420
  421 VIKLPFKYPE CMQAKDQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1g55A
Description: DNMT2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-methyltransferase activity 3.31632172292823 bayes_pls_golite062009
transferase activity 2.42370637689376 bayes_pls_golite062009
methyltransferase activity 2.24556320310886 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.1789895493932 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 2.17404404470337 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.06810685308813 bayes_pls_golite062009
catalytic activity 1.62377578202456 bayes_pls_golite062009
RNA methyltransferase activity 1.36067005317038 bayes_pls_golite062009
rRNA methyltransferase activity 0.740099749645209 bayes_pls_golite062009
DNA (cytosine-5-)-methyltransferase activity 0.6110460718981 bayes_pls_golite062009
N-methyltransferase activity 0.49575399394607 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 0.0680860762896796 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle