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Protein Overview: BIG2_ARATH

General Information:
Name(s) found: BIG2_ARATH [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Arabidopsis thaliana GN=BIG2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1793 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of ARF protein signal transduction [IEA]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEA]
    guanyl-nucleotide exchange factor activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSEADSRL SRVVTPALEK IVKNASWRKH SKLANECKAV IERLNSLQKS PPPSSSAATD  60
   61 SESESSVPGP LNDGGSIEYS LADSELIFSP LINACGTGLA KIIEPAIDCI QKLIAHGYIR 120
  121 GESDPSGGAE SLLLFKLIDS VCKCHDLGDE SIELPVLKTL LSAINSISLR IHGKCLLLVV 180
  181 RTCYDIYLGS KNVVNQTTAK ASLIQILVIV FRRMEADSST VPIQPIVVAE LMEPLEKSDA 240
  241 DGTMTQFVQG FITKIMQDID GVLNPTMSGS GSGSGSGGQD GAYGTTTVET TNPTDLLDST 300
  301 DKDMLDAKYW EISMYKSALE GRKGELTDGD AERDDDLEVQ IENKLRRDAC LVFRALCKLS 360
  361 MKAPPKESSA DPQSMRGKIL ALELLKILLE NAGAVFRTSE KFSADIKQFL CLSLLKNSAS 420
  421 TLMIIFQLSC SIFISLVARF RAGLKAEIGV FFPMIVLRVV ENVAQPNFQQ KMIVLRFLDK 480
  481 LCLDSQILVD IFLNYDCDVN SSNIFERMVN GLLKTAQGVP PGTATTLMPP QEAAMKLEAM 540
  541 KCLVAILKSM GDWLNKQLRL PVSNSLNKSD VIEIDLGPGS PQLANGNADE SADGSDTYSE 600
  601 SSGGTSDALA IEQRRAYKLE LQEGISLFNR KPTKGIEFLI NAGKVGESPE EIAGFLKDAS 660
  661 GLNKTLIGDY LGEREDLALK VMHAYVDSFD FRGMEFDEAI RTFLEGFRLP GEAQKIDRIM 720
  721 EKFAERYCKC NPKVFTSADS AYVLAYSVIM LNTDAHNPMV KNKMSADDFI RNNRGIDDGK 780
  781 DLPADYMRSL YERITKHEIK MKEDDLRLQQ KQYANSNRML GLDGILNIVI RKQWGDSYAE 840
  841 TSDDLMKHMQ EQFKEKARKS ESTYYAATDV VILRFMIEAC WAPMLAAFSV PLDQSDDLIV 900
  901 INICLEGFHH AIHATSLMSM KTHRDAFVTS LAKFTSLHSP ADIKQRNIEA IKAILRLADE 960
  961 EGNYLQDAWE HILTCVSRFE QLHLLGEGAP PDATFFASKQ NESEKSKQPK QYILPVLKRK1020
 1021 GPGKSQYAAT GVLRGSYDSM SLGGKGSKNV RQEQMSSIVS NLNLLEQVGE MNQVFSQSQK1080
 1081 LNSEAIIDFV KALCKVSMDE LRSPSNPRVF SLTKIVEIAH YNMNRIRLVW SSIWQVLSGF1140
 1141 FVTIGCSENL SIAIFAMDSL RQLSMKFLER EELANYNFQN EFMTPFVIVM RRSNDVEIRE1200
 1201 LIIRCVSQMV LSRVNNVKSG WKSMFMVFTT AAYDDHKNIV FLSFEIIEKI IREYFPYITE1260
 1261 TETTTFTDCV NCLVAFTNNR FSKDISLSSI AFLRYCATKL AEGDLNSPST NKYKGTSGKI1320
 1321 PQSSLHSGKS GKQENGEIVN NNHLYFWFPL LSGLSELSFD PRPEIRKSAL QIMFDTLRNH1380
 1381 GHLFSLPLWE KVFESVLFPI FDYVRHSIDP SGEDESADQG SSGGEVDELD HDAWLYETCT1440
 1441 LALQLVVDLF VKFYTTVNPL LEKVLMLLVS FIKRPHQSLA GIGIAAFVRL MSDADGLFSE1500
 1501 EKWLEVVSAL KEAAKTTCPD FSYFLSEEYV ARSQRSALNI QNSNAESAAP TATDGNEESQ1560
 1561 RTATHLYAAI SDAKCRAAVQ LLLIQAVMEI YNMYRPQLSA KNTLVLVDAL HGVALHAHGI1620
 1621 NSNTILRSRL QELGPMTQMQ DPPLLRLENE SYQICLTFLQ NLVADKTKKE EEEEEEEIES1680
 1681 LLVNICQEVL NFYIETSSSA KKLQSESSRA SEYRWRIPLG SGKRRELSAR APLIVATLQA1740
 1741 MCTLDEASFE KNLKCLFPLL ANLISCEHGS NEVQTALADM LGLSVGPVLL QWC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..225] MSA 1.113986 View MSA. No confident structure predictions are available.
    2 View Details [226..339] deduced N/A No confident structure predictions are available.
    3 View Details [340..600] MSA 1.223996 View MSA. No confident structure predictions are available.
    4 View Details [601..962] PSI-BLAST 84.221849 No description for 2r0dA was found.
    5 View Details [963..1051] deduced N/A No confident structure predictions are available.
    6 View Details [1052..1234] MSA 2.195988 View MSA. No confident structure predictions are available.
    7 View Details [1235..1361] deduced N/A No confident structure predictions are available.
    8 View Details [1362..1549] MSA 1.161993 View MSA. No confident structure predictions are available.
    9 View Details [1550..1620] deduced N/A No confident structure predictions are available.
    10 View Details [1621..1793] MSA 2.103983 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.58

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle