Protein Overview: HEM4_ARATH

General Information:
Name(s) found:	HEM4_ARATH [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|75219491\|sp\|O48721.2\|HEM4_ARATH RecName: Full=Uroporphyrinogen-III synthase, chloroplastic; Short=AtUROS; AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing]; AltName: Full=Uroporphyrinogen-III cosynthetase; Flags: Precursor [NCBI NR] gi\|20196944\|gb\|AAC14502.2\| expressed protein [Arabidopsis thaliana] [NCBI NR] gi\|18401160\|ref\|NP_565625.1\| HEMD; uroporphyrinogen-III synthase [Arabidopsis thaliana] [NCBI NR] gi\|109946587\|gb\|ABG48472.1\| At2g26540 [Arabidopsis thaliana] [NCBI NR] Uroporphyrinogen-III synthase, chloroplastic OS=Arabidopsis thaliana GN=UROS PE=2 SV=2 [Swiss-Prot] (O48721) Expressed protein [athaliana3702.FASTAC.txt] expressed protein [Arabidopsis thaliana]gi\|18401160\|ref\|NP_565625.1\| uroporphyrinogen-III synthase family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas] Tax_Id=3702 Uroporphyrinogen-III synthase family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta] \| Symbols: HEMD \| HEMD; uroporphyrinogen-III synthase \| chr2:11294744-11297302 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] expressed protein [Arabidopsis thaliana] [nr-271106-contam.fasta] At2g26540 [Arabidopsis thaliana] [nr-271106-contam.fasta] uroporphyrinogen-III synthase [Arabidopsis thaliana] [nr-271106-contam.fasta] \| Symbols: HEMD, UROS, ATUROS, ATDUF3, DUF3 \| uroporphyrinogen-III synthase family protein \| chr2:11287666-11290224 REVERSE LENGTH=321 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
Organism:	Arabidopsis thaliana
Length:	321 amino acids
Gene Ontology:
Cellular Component:	chloroplast [IDA]
Biological Process:	porphyrin biosynthetic process [ISS] uroporphyrinogen III biosynthetic process [IDA]
Molecular Function:	uroporphyrinogen-III synthase activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLLLSHCS ILSFQPPLSS SSSFHSSHIQ SLSKPVFASP SPIRNSISSS VSSSSSSVSS  60
   61 SNSIPQVVVT RERGKNNQII KALEKNGISS LELPLIQHAR GPDFDRLASV LNDKSFDWII 120
  121 ITSPEAGSVF LEAWKTASSP EVQIGVVGAG TARVFEEAMK SADGLLHVAF TPSKATGKVL 180
  181 ASELPEKVGK RSSVLYPASL KAGNDIVEGL SKRGFEVVRL NTYTTVPVQS VDTVLLQQAL 240
  241 SAPVLSVASP SAVRAWLHLI QNEEQWSNYV ACIGETTASA ARRLGLKNVY YPEKPGLEGW 300
  301 VESIMEALGA HADSSNPSSR N

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..62]	PSI-BLAST	6.0	Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
2	View Details	[63..321]	PSI-BLAST	45.09691	Uroporphyrinogen III synthase (U3S, HemD)

Protein Overview: HEM4_ARATH

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: