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Protein Overview: AL2C4_ARATH

General Information:
Name(s) found: AL2C4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|9294041|dbj|BAB01998.1| aldehyde dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|20530143|gb|AAM27004.1| aldehyde dehydrogenase ALDH1a [Arabidopsis thaliana] [NCBI NR]
  • gi|18404212|ref|NP_566749.1| ALDH2C4; 3-chloroallyl aldehyde dehydrogenase/ aldehyde dehydrogenase (NAD)/ coniferyl-aldehyde dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|15912241|gb|AAL08254.1| aldehyde dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|118595574|sp|Q56YU0.2|AL2C4_ARATH RecName: Full=Aldehyde dehydrogenase family 2 member C4; AltName: Full=ALDH1a; AltName: Full=Protein REDUCED EPIDERMAL FLUORESCENCE 1 [NCBI NR]
  • Aldehyde dehydrogenase family 2 member C4 OS=Arabidopsis thaliana GN=ALDH2C4 PE=1 SV=2 [Swiss-Prot]
  • (Q9LV57) Aldehyde dehydrogenase ALDH1a [athaliana3702.FASTAC.txt]
  • aldehyde dehydrogenase [Arabidopsis thaliana]gi|20530143|gb|AAM27004.1| aldehyde dehydrogenase ALDH1a [Arabidopsis thaliana]gi|15912241|gb|AAL08254.1| aldehyde dehydrogenase [Arabidopsis thaliana]gi|18404212|ref|NP_566749.1| aldehyde dehydrogenase (ALD [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Aldehyde dehydrogenase (ALDH1a) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ALDH1A, REF1, ALDH2C4 | ALDH2C4 (REDUCED EPIDERMAL FLUORESCENCE1); 3-chloroallyl aldehyde dehydrogenase/ aldehyde dehydrogenase (NAD) | chr3:8919739-8923036 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • aldehyde dehydrogenase ALDH1a [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • aldehyde dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ALDH2C4 (REDUCED EPIDERMAL FLUORESCENCE1); aldehyde dehydrogenase/ oxidoreductase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ALDH2C4, ALDH1A, REF1 | aldehyde dehydrogenase 2C4 | chr3:8919732-8923029 REVERSE LENGTH=501 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phenylpropanoid biosynthetic process [IDA]
    Molecular Function: aldehyde dehydrogenase (NAD) activity [ISS]
    3-chloroallyl aldehyde dehydrogenase activity [ISS]
    coniferyl-aldehyde dehydrogenase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENGKCNGAT TVKLPEIKFT KLFINGQFID AASGKTFETI DPRNGEVIAT IAEGDKEDVD  60
   61 LAVNAARYAF DHGPWPRMTG FERAKLINKF ADLIEENIEE LAKLDAVDGG KLFQLGKYAD 120
  121 IPATAGHFRY NAGAADKIHG ETLKMTRQSL FGYTLKEPIG VVGNIIPWNF PSIMFATKVA 180
  181 PAMAAGCTMV VKPAEQTSLS ALFYAHLSKE AGIPDGVLNI VTGFGSTAGA AIASHMDVDK 240
  241 VSFTGSTDVG RKIMQAAAAS NLKKVSLELG GKSPLLIFND ADIDKAADLA LLGCFYNKGE 300
  301 ICVASSRVFV QEGIYDKVVE KLVEKAKDWT VGDPFDSTAR QGPQVDKRQF EKILSYIEHG 360
  361 KNEGATLLTG GKAIGDKGYF IQPTIFADVT EDMKIYQDEI FGPVMSLMKF KTVEEGIKCA 420
  421 NNTKYGLAAG ILSQDIDLIN TVSRSIKAGI IWVNCYFGFD LDCPYGGYKM SGNCRESGMD 480
  481 ALDNYLQTKS VVMPLHNSPW M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..501] PSI-BLAST 178.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  4.35175408702761 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  4.2273960318884 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  2.78416888468693 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • acyl-CoA binding
    		•  2.26220696569489 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • retinoid binding
    		•  0.983782635681687 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.900374761028287 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle