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Protein Overview: ORP1A_ARATH

General Information:
Name(s) found: ORP1A_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|3201627|gb|AAC20736.1| putative oxysterol-binding protein [Arabidopsis thaliana] [NCBI NR]
  • pir||E84715 probable oxysterol-binding protein [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|15224597|ref|NP_180659.1| ORP1A (OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1A); oxysterol binding [Arabidopsis thaliana] [NCBI NR]
  • Oxysterol-binding protein-related protein 1A OS=Arabidopsis thaliana GN=ORP1A PE=2 SV=1 [Swiss-Prot]
  • (O80866) Putative oxysterol-binding protein [athaliana3702.FASTAC.txt]
  • putative oxysterol-binding protein [Arabidopsis thaliana]gi|15224597|ref|NP_180659.1| oxysterol-binding family protein [Arabidopsis thaliana]gi|25295692|pir||E84715 probable oxysterol-binding protein [imported] - Arabidopsis thaliana [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Oxysterol-binding family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | oxysterol-binding family protein | chr2:13208745-13211759 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative oxysterol-binding protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • oxysterol binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ORP1A | OSBP(oxysterol binding protein)-related protein 1A | chr2:13201668-13204682 FORWARD LENGTH=760 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 760 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid metabolic process [IEA][ISS]
    Molecular Function: oxysterol binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYAATPETPF GSARSQPVIT RSVSQRYNHP GQSNHHHLLH SLSFNHQNVL ALPAAAREPP  60
   61 VDVKINDIAG NSIAGILYKW VNYGKGWRPR WFVLQDGVLS YYKIKGPDKI VVIHETEKGS 120
  121 RVIGEESTRM ISRNKRHAAT NNTNHQLRRK PFGEVHLKVS SIRESRSDDK RFSIFTGTKR 180
  181 LHLRAETRED REAWIEALQA VKDMFPRMSN CELMAPTNNL DISIEKLRLR LVEEGVSESA 240
  241 IQDCEQITRS EFSAIQSQLL LLKQKQWLLI DTLRQLETEK VDLENTVVDE TQRQAGNGDS 300
  301 EETISESDDD NEQFDEAEEE MDTCDSLSSS SFKSIGSVFR TSSFSSDDDG LTNGFESEND 360
  361 DVDPSIKTIG FNYPHVKRRK KLPDPVEKEK SVSLWSMIKD NIGKDLTKVC LPVYFNEPLS 420
  421 SLQKCFEDLE YSYLLDQASE WGKRGNNLMR ILNVAAFAVS GYASTEGRIC KPFNPMLGET 480
  481 YEADYPDKGL RFFSEKVSHH PMIVACHCDG TGWKFWGDSN LKSKFWGRSI QLDPIGLLTL 540
  541 QFDDGEIVQW SKVTTSIYNL ILGKLYCDHY GTMKIEGNGE YSCKLKFKEQ SMIDRNPHQV 600
  601 QGIVEDKNGK TVARLFGKWD ESIHYVMVDQ GKVNESHLLW KRNKQPENPT KYNLTRFGIT 660
  661 LNELTPGLKE KLPPTDSRLR PDQRYLEKGE YEMGNAEKLR LEQRQRQARE MQERGWKPKW 720
  721 FRKEKGSETY RYIGGYWEAR DSGSWDDCPD IFGQVHQSIK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 15.09691 Grp1
    2 View Details [212..389] deduced N/A No confident structure predictions are available.
    3 View Details [390..760] PSI-BLAST 65.221849 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.42470476396787 bayes_pls_golite062009
  • protein binding
    		•  2.1446140694885 bayes_pls_golite062009
  • receptor binding
    		•  0.3173431866346 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle