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View Structure Prediction Details

Protein: ORP1A_ARATH
Organism: Arabidopsis thaliana
Length: 760 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORP1A_ARATH.

Description E-value Query
Range
Subject
Range
ORP1C_ARATH - Oxysterol-binding protein-related protein 1C OS=Arabidopsis thaliana GN=ORP1C PE=2 SV=1
553.0 [0..10] [760..34]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYAATPETPF GSARSQPVIT RSVSQRYNHP GQSNHHHLLH SLSFNHQNVL ALPAAAREPP  60
   61 VDVKINDIAG NSIAGILYKW VNYGKGWRPR WFVLQDGVLS YYKIKGPDKI VVIHETEKGS 120
  121 RVIGEESTRM ISRNKRHAAT NNTNHQLRRK PFGEVHLKVS SIRESRSDDK RFSIFTGTKR 180
  181 LHLRAETRED REAWIEALQA VKDMFPRMSN C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.09691
Match: 1fhwA
Description: Grp1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42470476396787 bayes_pls_golite062009
protein binding 2.1446140694885 bayes_pls_golite062009
receptor binding 0.3173431866346 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [212-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELMAPTNNLD ISIEKLRLRL VEEGVSESAI QDCEQITRSE FSAIQSQLLL LKQKQWLLID  60
   61 TLRQLETEKV DLENTVVDET QRQAGNGDSE ETISESDDDN EQFDEAEEEM DTCDSLSSSS 120
  121 FKSIGSVFRT SSFSSDDDGL TNGFESENDD VDPSIKTIGF NYPHVKRRKK LPDPVEKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [390-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSVSLWSMIK DNIGKDLTKV CLPVYFNEPL SSLQKCFEDL EYSYLLDQAS EWGKRGNNLM  60
   61 RILNVAAFAV SGYASTEGRI CKPFNPMLGE TYEADYPDKG LRFFSEKVSH HPMIVACHCD 120
  121 GTGWKFWGDS NLKSKFWGRS IQLDPIGLLT LQFDDGEIVQ WSKVTTSIYN LILGKLYCDH 180
  181 YGTMKIEGNG EYSCKLKFKE QSMIDRNPHQ VQGIVEDKNG KTVARLFGKW DESIHYVMVD 240
  241 QGKVNESHLL WKRNKQPENP TKYNLTRFGI TLNELTPGLK EKLPPTDSRL RPDQRYLEKG 300
  301 EYEMGNAEKL RLEQRQRQAR EMQERGWKPK WFRKEKGSET YRYIGGYWEA RDSGSWDDCP 360
  361 DIFGQVHQSI K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.221849
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle