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Protein Overview: ORP1C_ARATH

General Information:
Name(s) found: ORP1C_ARATH [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Oxysterol-binding protein-related protein 1C OS=Arabidopsis thaliana GN=ORP1C PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 814 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: signal transduction [ISS]
    steroid metabolic process [ISS]
    Molecular Function: oxysterol binding [ISS]
    phosphoinositide binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPFCCVTTV SDHSPSMPPL PEPQPPLPNY AADFGSARSE PIITRSASQS YNHSGQFNNN  60
   61 LIHSLSFNHH QSDVTDRLGQ RVLALPAAVR EPPVDVKIND IVGNGIAGIL YKWVNYGRGW 120
  121 RPRWFVLQDG VLSYYKIHGP DKIFVSPETE KGSKVIGDES ARMISRHNRR GGSSSSCQLR 180
  181 RKPFGEVHLK VSSVRESRSD DKRFSIFTGT KRLHLRAETR EDRTTWVEAL QAVKDMFPRM 240
  241 SNSELMAPTN NLAMSTEKIR LRLIEEGVSE LAIQDCEQIM KSEFSALQSQ LVLLKQKQWL 300
  301 LIDTLRQLET EKVDLENTVV DESQRQADNG CSGELRHEKF SEGTATESDD DNERGDAAEE 360
  361 EFDEEENTFF DTRDFLSSSS FKSSGSGFRT SSFSSDEDGF ESEDDIDPSI KSIGCNYPRV 420
  421 KRRKNLPDPV EKEKSVSLWS MIKDNIGKDL TKVCLPVYFN EPLSSLQKCF EDLEYSYLLD 480
  481 RAFEYGKRGN SLMRILNVAA FAVSGYASTE GRICKPFNPL LGETYEADYP DKGLRFFSEK 540
  541 VSHHPMVVAC HCDGTGWKFW GDSNLRSKFW GRSIQLDPVG VLTLQFDDGE ILQWSKVTTS 600
  601 IYNLILGKLY CDHYGTMRIE GSAEYSCKLK FKEQSIIDRN PHQVHGIVQN KSGKTVATMF 660
  661 GKWDESIHFV TGDCSGKGKL SEDMSGAQLL WKRSKPPGNA TKYNLTRFAI TLNELTPGLK 720
  721 ERLPPTDSRL RPDQRYLENG EFEMANTEKL RLEQRQRQAR KMQERGWKPR WFMKEKGSES 780
  781 YRYKGGYWEA REDGSWVDCP DIFGHIDSDQ QMIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..283] PSI-BLAST 13.522879 Crystal Structure of the PH Domain of SKAP-Hom with 8 Vector-derived N-terminal Residues
    3 View Details [284..428] deduced N/A No confident structure predictions are available.
    4 View Details [429..814] PSI-BLAST 70.522879 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle