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Protein Overview: THD1_ARATH

General Information:
Name(s) found: THD1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|6942237|gb|AAF32370.1|AF221984_1 threonine dehydratase/deaminase [Arabidopsis thaliana] [NCBI NR]
  • gi|6143871|gb|AAF04418.1|AC010927_11 threonine dehydratase/deaminase (OMR1) [Arabidopsis thaliana] [NCBI NR]
  • gi|3800878|gb|AAC97936.1| threonine dehydratase/deaminase [Arabidopsis thaliana] [NCBI NR]
  • gi|18086439|gb|AAL57674.1| AT3g10050/T22K18_12 [Arabidopsis thaliana] [NCBI NR]
  • gi|17369978|sp|Q9ZSS6.1|THD1_ARATH RecName: Full=Threonine dehydratase biosynthetic, chloroplastic; AltName: Full=Threonine deaminase; Short=TD; Flags: Precursor [NCBI NR]
  • gi|15232827|ref|NP_187616.1| OMR1 (L-O-METHYLTHREONINE RESISTANT 1); L-threonine ammonia-lyase [Arabidopsis thaliana] [NCBI NR]
  • pir||T51712 threonine ammonia-lyase (EC 4.3.1.19) [similarity] - Arabidopsis thaliana [NCBI NR]
  • Threonine dehydratase biosynthetic, chloroplastic OS=Arabidopsis thaliana GN=OMR1 PE=1 SV=1 [Swiss-Prot]
  • (Q9ZSS6) Threonine dehydratase biosynthetic, chloroplast precursor (EC 4.3.1.19) (Threonine deaminase) (TD) [athaliana3702.FASTAC.txt]
  • threonine dehydratase/deaminase (OMR1) [Arabidopsis thaliana]gi|18086439|gb|AAL57674.1| AT3g10050/T22K18_12 [Arabidopsis thaliana]gi|6942237|gb|AAF32370.1| threonine dehydratase/deaminase [Arabidopsis thaliana]gi|3800878|gb|AAC97936.1| threonine dehydr [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Threonine dehydratase biosynthetic, chloroplast precursor [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: OMR1 | OMR1 (L-O-METHYLTHREONINE RESISTANT 1); L-threonine ammonia-lyase | chr3:3099169-3101746 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • OMR1 (L-O-METHYLTHREONINE RESISTANT 1); catalytic/ threonine ammonia-lyase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • threonine dehydratase/deaminase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Threonine dehydratase biosynthetic, chloroplast precursor (Threonine deaminase) (TD) [nr-271106-contam.fasta]
  • AT3g10050/T22K18_12 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • threonine dehydratase/deaminase (OMR1) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: OMR1 | L-O-methylthreonine resistant 1 | chr3:3099164-3101741 REVERSE LENGTH=592 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 592 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IEA]
    Biological Process: isoleucine biosynthetic process [TAS]
    threonine metabolic process [ISS]
    Molecular Function: L-threonine ammonia-lyase activity [IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSVQLPTAQ SSLRSHIHRP SKPVVGFTHF SSRSRIAVAV LSRDETSMTP PPPKLPLPRL  60
   61 KVSPNSLQYP AGYLGAVPER TNEAENGSIA EAMEYLTNIL STKVYDIAIE SPLQLAKKLS 120
  121 KRLGVRMYLK REDLQPVFSF KLRGAYNMMV KLPADQLAKG VICSSAGNHA QGVALSASKL 180
  181 GCTAVIVMPV TTPEIKWQAV ENLGATVVLF GDSYDQAQAH AKIRAEEEGL TFIPPFDHPD 240
  241 VIAGQGTVGM EITRQAKGPL HAIFVPVGGG GLIAGIAAYV KRVSPEVKII GVEPADANAM 300
  301 ALSLHHGERV ILDQVGGFAD GVAVKEVGEE TFRISRNLMD GVVLVTRDAI CASIKDMFEE 360
  361 KRNILEPAGA LALAGAEAYC KYYGLKDVNV VAITSGANMN FDKLRIVTEL ANVGRQQEAV 420
  421 LATLMPEKPG SFKQFCELVG PMNISEFKYR CSSEKEAVVL YSVGVHTAGE LKALQKRMES 480
  481 SQLKTVNLTT SDLVKDHLRY LMGGRSTVGD EVLCRFTFPE RPGALMNFLD SFSPRWNITL 540
  541 FHYRGQGETG ANVLVGIQVP EQEMEEFKNR AKALGYDYFL VSDDDYFKLL MH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 89.30103 Cystathionine beta-synthase
    2 View Details [85..592] PSI-BLAST 153.0 THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • acetolactate synthase activity
    		•  6.50887202511626 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  5.28856942236052 bayes_pls_golite062009
  • threonine racemase activity
    		•  4.44340924206787 bayes_pls_golite062009
  • threonine synthase activity
    		•  3.59927532963055 bayes_pls_golite062009
  • cysteine synthase activity
    		•  3.57860549303214 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  3.33109959091277 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • binding
    		•  1.14906798355281 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • catalytic activity
    		•  0.645256181736122 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • protein binding
    		•  0.341967829237094 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.248470717905239 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle