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Protein Overview: NIP21_ARATH

General Information:
Name(s) found: NIP21_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7449723|pir||T02327 nodulin-26 homolog F13P17.23 - Arabidopsis thaliana [NCBI NR]
  • gi|56783485|emb|CAC81707.2| aquaporin NIP2.1 [Arabidopsis thaliana] [NCBI NR]
  • gi|32363364|sp|Q8W037.2|NIP21_ARATH RecName: Full=Aquaporin NIP2-1; AltName: Full=NOD26-like intrinsic protein 2-1; Short=AtNIP2;1; AltName: Full=Nodulin-26-like major intrinsic protein 4; Short=NodLikeMip4; Short=Protein NLM4 [NCBI NR]
  • gi|3128232|gb|AAC26712.1| putative aquaporin (plasma membrane intrinsic protein) [Arabidopsis thaliana] [NCBI NR]
  • gi|20197165|gb|AAM14952.1| putative aquaporin (plasma membrane intrinsic protein) [Arabidopsis thaliana] [NCBI NR]
  • gi|15226298|ref|NP_180986.1| NIP2;1 (NOD26-LIKE INTRINSIC PROTEIN 2;1); lactate transmembrane transporter/ water channel [Arabidopsis thaliana] [NCBI NR]
  • gi|106879199|gb|ABF82629.1| At2g34390 [Arabidopsis thaliana] [NCBI NR]
  • Aquaporin NIP2-1 OS=Arabidopsis thaliana GN=NIP2-1 PE=2 SV=2 [Swiss-Prot]
  • (Q8W037) Aquaporin NIP2.1 (NOD26-like intrinsic protein 2.1) (Nodulin-26-like major intrinsic protein 4) (AtNLM4) (NLM4 protein) (NodLikeMip4) [Swiss-Prot]
  • putative aquaporin (plasma membrane intrinsic protein) [Arabidopsis thaliana]gi|3128232|gb|AAC26712.1| putative aquaporin (plasma membrane intrinsic protein) [Arabidopsis thaliana]gi|32363364|sp|Q8W037|NI21_ARATH Aquaporin NIP2.1 (NOD26-like intrinsic p [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Aquaporin NIP2.1 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: NIP2;1, NLM4 | NIP2;1/NLM4 (NOD26-LIKE INTRINSIC PROTEIN 2;1); lactate transmembrane transporter/ water channel | chr2:14521696-14522872 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At2g34390 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • water channel [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • aquaporin NIP2.1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative aquaporin (plasma membrane intrinsic protein) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • nodulin-26 homolog F13P17.23 - Arabidopsis thaliana [nr-271106-contam.fasta]
  • Aquaporin NIP2.1 (NOD26-like intrinsic protein 2.1) (Nodulin-26-like major intrinsic protein 4) (AtNLM4) (Protein NLM4) (NodLikeMip4) [nr-271106-contam.fasta]
  • | Symbols: NIP2;1, NLM4 | NOD26-like intrinsic protein 2;1 | chr2:14514617-14515793 REVERSE LENGTH=288 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 288 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISS]
    endoplasmic reticulum [IDA]
    plasma membrane [IDA]
    Biological Process: response to hypoxia [IEP]
    lactate transport [IDA]
    transport [ISS]
    Molecular Function: water channel activity [ISS]
    lactate transmembrane transporter activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDISVSKSN HGNVVVLNIK ASSLADTSLP SNKHESSSPP LLSVHFLQKL LAELVGTYYL  60
   61 IFAGCAAIAV NAQHNHVVTL VGIAVVWGIV IMVLVYCLGH LSAHFNPAVT LALASSQRFP 120
  121 LNQVPAYITV QVIGSTLASA TLRLLFDLNN DVCSKKHDVF LGSSPSGSDL QAFVMEFIIT 180
  181 GFLMLVVCAV TTTKRTTEEL EGLIIGATVT LNVIFAGEVS GASMNPARSI GPALVWGCYK 240
  241 GIWIYLLAPT LGAVSGALIH KMLPSIQNAE PEFSKTGSSH KRVTDLPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 61.69897 Crystal structure of the spinach aquaporin SoPIP2;1 in an open conformation to 3.9 resolution


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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