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Protein Overview: ICS1_ARATH

General Information:
Name(s) found: ICS1_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Isochorismate synthase 1, chloroplastic OS=Arabidopsis thaliana GN=ICS1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 569 amino acids

    Gene Ontology:
    Cellular Component: plastid [IDA][ISS]
    Biological Process: response to bacterium [IMP]
    systemic acquired resistance [IEP][IMP]
    phylloquinone biosynthetic process [IMP]
    salicylic acid biosynthetic process [IMP][TAS]
    stomatal movement [IMP]
    defense response to fungus [IMP]
    negative regulation of defense response [IMP]
    defense response to bacterium [IMP]
    Molecular Function: isochorismate synthase activity [IMP][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLQFSSQF LGSNTKTHSS IISISRSYSP TPFTRFSRKK YESCSMSMNG CDGDFKTPLG  60
   61 TVETRTMTAV LSPAAATERL ISAVSELKSQ PPSFSSGVVR LQVPIDQQIG AIDWLQAQNE 120
  121 IQPRCFFSRR SDVGRPDLLL DLANENGNGN GNGTVSSDRN LVSVAGIGSA VFFRDLDPFS 180
  181 HDDWRSIRRF LSSTSPLIRA YGGMRFDPNG KIAVEWEPFG AFYFSVPQVE FNEFGGSSML 240
  241 AATIAWDDEL SWTLENAIEA LQETMLQVSS VVMKLRNRSL GVSVLSKNHV PTKGAYFPAV 300
  301 EKALEMINQK SSPLNKVVLA RNSRIITDTD IDPIAWLAQL QREGHDAYQF CLQPPGAPAF 360
  361 IGNTPERLFQ RTQLGVCSEA LAATRPRAAS SARDMEIERD LLTSPKDDLE FSIVRENIRE 420
  421 KLNGICDRVV VKPQKTVRKL ARVQHLYSQL AGRLTKEDDE YKILAALHPT PAVCGLPAEE 480
  481 ARLLIKEIES FDRGMYAGPI GFFGGEESEF AVGIRSALVE KGLGALIYAG TGIVAGSDPS 540
  541 SEWNELDLKI SQFTKSIEYE ATTSLQAIN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..569] PSI-BLAST 114.0 Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.48154800529305 bayes_pls_golite062009
  • isochorismate synthase activity
    		•  2.12058677071834 bayes_pls_golite062009
  • intramolecular transferase activity, transferring hydroxy groups
    		•  2.12058677071834 bayes_pls_golite062009
  • oxo-acid-lyase activity
    		•  1.49234742790531 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.18272988873809 bayes_pls_golite062009
  • 4-amino-4-deoxychorismate synthase activity
    		•  1.13392130624907 bayes_pls_golite062009
  • anthranilate synthase activity
    		•  0.47805305233277 bayes_pls_golite062009
  • lyase activity
    		•  0.151487106592176 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle