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View Structure Prediction Details

Protein: ICS1_ARATH
Organism: Arabidopsis thaliana
Length: 569 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ICS1_ARATH.

Description E-value Query
Range
Subject
Range
gi|48845511, gi|... - gi|78223698|ref|YP_385445.1| anthranilate synthase, component I [Geobacter metallireducens GS-15], g...
502.0 [0..105] [561..19]

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Predicted Domain #1
Region A:
Residues: [1-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLQFSSQF LGSNTKTHSS IISISRSYSP TPFTRFSRKK YESCSMSMNG CDGDFKTPLG  60
   61 TVETRTMTAV LSPAAATERL ISAVSELKSQ PPSFSSGVVR LQVPIDQQIG AIDWLQAQNE 120
  121 IQPRCFFSRR SDVGRPDLLL DLANENGNGN GNGTVSSDRN LVSVAGIGSA VFFRDLDPFS 180
  181 HDDWRSIRRF LSSTSPLIRA YGGMRFDPNG KIAVEWEPFG AFYFSVPQVE FNEFGGSSML 240
  241 AATIAWDDEL SWTLENAIEA LQETMLQVSS VVMKLRNRSL GVSVLSKNHV PTKGAYFPAV 300
  301 EKALEMINQK SSPLNKVVLA RNSRIITDTD IDPIAWLAQL QREGHDAYQF CLQPPGAPAF 360
  361 IGNTPERLFQ RTQLGVCSEA LAATRPRAAS SARDMEIERD LLTSPKDDLE FSIVRENIRE 420
  421 KLNGICDRVV VKPQKTVRKL ARVQHLYSQL AGRLTKEDDE YKILAALHPT PAVCGLPAEE 480
  481 ARLLIKEIES FDRGMYAGPI GFFGGEESEF AVGIRSALVE KGLGALIYAG TGIVAGSDPS 540
  541 SEWNELDLKI SQFTKSIEYE ATTSLQAIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1i1qA
Description: Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.48154800529305 bayes_pls_golite062009
isochorismate synthase activity 2.12058677071834 bayes_pls_golite062009
intramolecular transferase activity, transferring hydroxy groups 2.12058677071834 bayes_pls_golite062009
oxo-acid-lyase activity 1.49234742790531 bayes_pls_golite062009
carbon-carbon lyase activity 1.18272988873809 bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity 1.13392130624907 bayes_pls_golite062009
anthranilate synthase activity 0.47805305233277 bayes_pls_golite062009
lyase activity 0.151487106592176 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle