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Protein Overview: HGD_ARATH

General Information:
Name(s) found: HGD_ARATH [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Homogentisate 1,2-dioxygenase OS=Arabidopsis thaliana GN=HGO PE=2 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 461 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: L-phenylalanine catabolic process [IEA][ISS]
    tyrosine metabolic process [IEA]
    tyrosine catabolic process [ISS]
    Molecular Function: homogentisate 1,2-dioxygenase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKKKELEE LKYQSGFGNH FSSEAIAGAL PLDQNSPLLC PYGLYAEQIS GTSFTSPRKL  60
   61 NQRSWLYRVK PSVTHEPFKP RVPAHKKLVS EFDASNSRTN PTQLRWRPED IPDSEIDFVD 120
  121 GLFTICGAGS SFLRHGFAIH MYVANTGMKD SAFCNADGDF LLVPQTGRLW IETECGRLLV 180
  181 TPGEIAVIPQ GFRFSIDLPD GKSRGYVAEI YGAHFQLPDL GPIGANGLAA SRDFLAPTAW 240
  241 FEDGLRPEYT IVQKFGGELF TAKQDFSPFN VVAWHGNYVP YKYDLKKFCP YNTVLLDHGD 300
  301 PSINTVLTAP TDKPGVALLD FVIFPPRWLV AEHTFRPPYY HRNCMSEFMG LIYGAYEAKA 360
  361 DGFLPGGASL HSCMTPHGPD TTTYEATIAR VNAMAPSKLT GTMAFMFESA LIPRVCHWAL 420
  421 ESPFLDHDYY QCWIGLKSHF SRISLDKTNV ESTEKEPGAS E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..461] PSI-BLAST 1000.0 Homogentisate dioxygenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
    		•  2.65960759413149 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
    		•  2.611114803333 bayes_pls_golite062009
  • homogentisate 1,2-dioxygenase activity
    		•  2.36574960723119 bayes_pls_golite062009
  • dioxygenase activity
    		•  0.930778069601015 bayes_pls_golite062009
  • catalytic activity
    		•  0.401988496917198 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle