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Protein Overview: HMA4_ARATH

General Information:
Name(s) found: HMA4_ARATH [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Putative cadmium/zinc-transporting ATPase HMA4 OS=Arabidopsis thaliana GN=HMA4 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1172 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA][TAS]
    Biological Process: zinc ion transport [IMP]
    cadmium ion transport [IMP]
    Molecular Function: cadmium-transporting ATPase activity [ISS]
    protein binding [IPI]
    cadmium ion transmembrane transporter activity [IGI]
    zinc ion transmembrane transporter activity [IGI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALQNKEEEK KKVKKLQKSY FDVLGICCTS EVPIIENILK SLDGVKEYSV IVPSRTVIVV  60
   61 HDSLLISPFQ IAKALNEARL EANVRVNGET SFKNKWPSPF AVVSGLLLLL SFLKFVYSPL 120
  121 RWLAVAAVAA GIYPILAKAF ASIKRPRIDI NILVIITVIA TLAMQDFMEA AAVVFLFTIS 180
  181 DWLETRASYK ATSVMQSLMS LAPQKAIIAE TGEEVEVDEV KVDTVVAVKA GETIPIDGIV 240
  241 VDGNCEVDEK TLTGEAFPVP KQRDSTVWAG TINLNGYICV KTTSLAGDCV VAKMAKLVEE 300
  301 AQSSKTKSQR LIDKCSQYYT PAIILVSACV AIVPVIMKVH NLKHWFHLAL VVLVSGCPCG 360
  361 LILSTPVATF CALTKAATSG LLIKSADYLD TLSKIKIVAF DKTGTITRGE FIVIDFKSLS 420
  421 RDINLRSLLY WVSSVESKSS HPMAATIVDY AKSVSVEPRP EEVEDYQNFP GEGIYGKIDG 480
  481 NDIFIGNKKI ASRAGCSTVP EIEVDTKGGK TVGYVYVGER LAGFFNLSDA CRSGVSQAMA 540
  541 ELKSLGIKTA MLTGDNQAAA MHAQEQLGNV LDVVHGDLLP EDKSRIIQEF KKEGPTAMVG 600
  601 DGVNDAPALA TADIGISMGI SGSALATQTG NIILMSNDIR RIPQAVKLAR RARRKVVENV 660
  661 CLSIILKAGI LALAFAGHPL IWAAVLVDVG TCLLVIFNSM LLLREKKKIG NKKCYRASTS 720
  721 KLNGRKLEGD DDYVVDLEAG LLTKSGNGQC KSSCCGDKKN QENVVMMKPS SKTSSDHSHP 780
  781 GCCGDKKEEK VKPLVKDGCC SEKTRKSEGD MVSLSSCKKS SHVKHDLKMK GGSGCCASKN 840
  841 EKGKEVVAKS CCEKPKQQVE SVGDCKSGHC EKKKQAEDIV VPVQIIGHAL THVEIELQTK 900
  901 ETCKTSCCDS KEKVKETGLL LSSENTPYLE KGVLIKDEGN CKSGSENMGT VKQSCHEKGC 960
  961 SDEKQTGEIT LASEEETDDQ DCSSGCCVNE GTVKQSFDEK KHSVLVEKEG LDMETGFCCD1020
 1021 AKLVCCGNTE GEVKEQCRLE IKKEEHCKSG CCGEEIQTGE ITLVSEEETE STNCSTGCCV1080
 1081 DKEEVTQTCH EKPASLVVSG LEVKKDEHCE SSHRAVKVET CCKVKIPEAC ASKCRDRAKR1140
 1141 HSGKSCCRSY AKELCSHRHH HHHHHHHHHV SA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..682] PSI-BLAST 127.0 No description for 3b8eA was found.
    2 View Details [683..776] PSI-BLAST 4.522879 No description for 3dslA was found.
    3 View Details [777..1172] PSI-BLAST 26.0 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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