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Protein Overview: 1A12_ARATH

General Information:
Name(s) found: 1A12_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|8920586|gb|AAF81308.1|AC061957_4 Identical to 1-aminocyclopropane-1-carboxylate synthase (ASC2) from Arabidopsis thaliana gb|M95594 and contains an aminotransferases class-I PF|00155 domain. EST gb|BE038138 comes from this gene [NCBI NR]
  • gi|543712|sp|Q06402.1|1A12_ARATH RecName: Full=1-aminocyclopropane-1-carboxylate synthase 2; Short=ACC synthase 2; AltName: Full=S-adenosyl-L-methionine methylthioadenosine-lyase 2 [NCBI NR]
  • pir||A47199 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) - Arabidopsis thaliana [NCBI NR]
  • gi|2505881|emb|CAA73310.1| ACC-synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|166580|gb|AAB59298.1| 1-aminocyclopropane-1-carboxylate synthase [NCBI NR]
  • gi|16148|emb|CAA78260.1| 1-aminocyclopropane 1-carboxylate synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|15223414|ref|NP_171655.1| ACS2; 1-aminocyclopropane-1-carboxylate synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|12248011|gb|AAG50097.1|AF334719_1 1-aminocyclopropane-1-carboxylate synthase ACS2 [Arabidopsis thaliana] [NCBI NR]
  • 1-aminocyclopropane-1-carboxylate synthase 2 OS=Arabidopsis thaliana GN=ACS2 PE=1 SV=1 [Swiss-Prot]
  • (Q06402) 1-aminocyclopropane-1-carboxylate synthase 2 (EC 4.4.1.14) (ACC synthase 2) (S-adenosyl-L-methionine methylthioadenosine-lyase 2) [athaliana3702.FASTAC.txt]
  • 1-aminocyclopropane-1-carboxylate synthase ACS2 [Arabidopsis thaliana]gi|2505881|emb|CAA73310.1| ACC-synthase [Arabidopsis thaliana]gi|16148|emb|CAA78260.1| 1-aminocyclopropane 1-carboxylate synthase [Arabidopsis thaliana]gi|166580|gb|AAB59298.1| 1-ami [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Splice Isoform 1 of 1-aminocyclopropane-1-carboxylate synthase 2 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: AT-ACC2, ACS2 | ACS2 (1-Amino-cyclopropane-1-carboxylate synthase 2) | chr1:175862-178051 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • 1-aminocyclopropane 1-carboxylate synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 1-aminocyclopropane-1-carboxylate synthase 2 (ACC synthase 2) (S-adenosyl-L-methionine methylthioadenosine-lyase 2) [nr-271106-contam.fasta]
  • Identical to 1-aminocyclopropane-1-carboxylate synthase (ASC2) from Arabidopsis thaliana gb|M95594 and contains an aminotransferases class-I PF|00155 domain. EST gb|BE038138 comes from this gene [nr-271106-contam.fasta]
  • ACS2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 1-aminocyclopropane-1-carboxylate synthase ACS2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ACC-synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 1-aminocyclopropane-1-carboxylate synthase [nr-271106-contam.fasta]
  • | Symbols: ACS2, AT-ACC2 | 1-amino-cyclopropane-1-carboxylate synthase 2 | chr1:175862-178051 FORWARD LENGTH=496 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: ethylene biosynthetic process [TAS]
    Molecular Function: 1-aminocyclopropane-1-carboxylate synthase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLPGKNKGA VLSKIATNNQ HGENSEYFDG WKAYDKDPFH LSRNPHGIIQ MGLAENQLCL  60
   61 DLIKDWVKEN PEASICTLEG IHQFSDIANF QDYHGLKKFR QAIAHFMGKA RGGRVTFDPE 120
  121 RVVMSGGATG ANETIMFCLA DPGDVFLIPS PYYAAFDRDL RWRTGVEIIP VPCSSSDNFK 180
  181 LTVDAAEWAY KKAQESNKKV KGLILTNPSN PLGTMLDKDT LTNLVRFVTR KNIHLVVDEI 240
  241 YAATVFAGGD FVSVAEVVND VDISEVNVDL IHIVYSLSKD MGLPGFRVGI VYSFNDSVVS 300
  301 CARKMSSFGL VSSQTQLMLA SMLSDDQFVD NFLMESSRRL GIRHKVFTTG IKKADIACLT 360
  361 SNAGLFAWMD LRHLLRDRNS FESEIELWHI IIDRVKLNVS PGSSFRCTEP GWFRICFANM 420
  421 DDDTLHVALG RIQDFVSKNK NKIVEKASEN DQVIQNKSAK KLKWTQTNLR LSFRRLYEDG 480
  481 LSSPGIMSPH SPLLRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..435] PSI-BLAST 107.0 1-aminocyclopropane-1-carboxylate synthase (ACC synthase)
    2 View Details [436..496] MSA 2.804993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  4.43277563699654 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transferase activity
    		•  0.737426388870721 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  0.390162083170876 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  0.390162083170876 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle