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Protein Overview: SUMT_BACSU

General Information:
Name(s) found: SUMT_BACSU [Swiss-Prot]
Description(s) found:
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  • gi|81637597|sp|O34744.1|SUMT_BACSU RecName: Full=Uroporphyrinogen-III C-methyltransferase; Short=Urogen III methylase; AltName: Full=SUMT; AltName: Full=Uroporphyrinogen III methylase; Short=UROM [NCBI NR]
  • pir||D69877 uroporphyrin-III C-methyltransferase homolog ylnD - Bacillus subtilis [NCBI NR]
  • gi|2462960|emb|CAA04413.1| putative S-adenosyl L-methionine: uroporphyrinogen III methyltransferase [Bacillus subtilis] [NCBI NR]
  • Uroporphyrinogen-III C-methyltransferase OS=Bacillus subtilis GN=sumT PE=2 SV=1 [Swiss-Prot]
  • 257 aa - unknown; similar to uroporphyrin-III C-methyltransferase [subtilist_Price.fasta]
  • hypothetical protein BSU15610 [Bacillus subtilis subsp. subtilis str. 168]gi|2462960|emb|CAA04413.1| putative S-adenosyl L-methionine: uroporphyrinogen III methyltransferase [Bacillus subtilis]gi|2633934|emb|CAB13435.1| ylnD [Bacillus subtilis subsp. su [nrdb_11152004_Chlamydomonas]
  • Uroporphyrinogen-III C-methyltransferase OS=Bacillus subtilis (strain 168) GN=sumT PE=2 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Bacillus subtilis
    Length: 257 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVYIVGAG PGDPDLLTIK ALKAIEKADV ILYDRLVNKE ILQYAKEQAD LIYCGKLPDF  60
   61 HTMKQETINR FLVKYAQKGK MVVRLKGGDP FVFGRGGEEA ECLSENGIPF EIIPGITSGI 120
  121 AAAAYAGIPV THRDAGSNVA FVTGHYKKEE DFEEKWKALA TGIDTLVIYM GIKNVQQIER 180
  181 KLLENGRDGS TPAAFIHWGT TDKQKSVFCT VDTLSETVIK ENITNPSLIV IGNVVNYHYK 240
  241 LEWFESELKK QDLSEAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..257] PSI-BLAST 71.154902 Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrin-III C-methyltransferase activity
    		•  3.573271502205 bayes_pls_golite062009
  • C-methyltransferase activity
    		•  3.35393353163232 bayes_pls_golite062009
  • precorrin-4 C11-methyltransferase activity
    		•  2.18371138649366 bayes_pls_golite062009
  • catalytic activity
    		•  1.48349578618275 bayes_pls_golite062009
  • transferase activity
    		•  0.912524944496351 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.431791521097299 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.424918406685891 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.28351517300952 bayes_pls_golite062009
  • uroporphyrinogen-III synthase activity
    		•  0.00871858903098705 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle