Protein Overview: gcn2

General Information:
Name(s) found:	gcn2 / SPBC36B7.09 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	gi\|63054755\|ref\|NP_595991.2\| eIF2 alpha kinase Gcn2 (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR] gi\|51860125\|gb\|AAU11313.1\| Gcn2 [Schizosaccharomyces pombe] [NCBI NR] gi\|46396516\|sp\|Q9HGN1.2\|GCN2_SCHPO RecName: Full=Serine/threonine-protein kinase gcn2; AltName: Full=Serine/threonine-protein kinase ppk28 [NCBI NR] gi\|157310427\|emb\|CAC05730.2\| eIF2 alpha kinase Gcn2 [Schizosaccharomyces pombe] [NCBI NR] eIF2 alpha kinase Gcn2 [Sanger Pombe] (Q9HGN1) Probable serine/threonine-protein kinase C36B7.09 (EC 2.7.1.37) [Swiss-Prot] Serine/threonine-protein kinase gcn2 OS=Schizosaccharomyces pombe GN=gcn2 PE=2 SV=2 [Swiss-Prot] PUTATIVE EIF-2ALPHA KINASE; POSSIBLY INVOLVED IN INVOLVED IN GENERAL AMINO ACID CONTROL RESPONSE BY SIMILAR TO S. CEREVISIAE GCN2: Q9HDW2;Q9HGN1; [pompepVF.fasta] PUTATIVE EIF-2ALPHA KINASE; POSSIBLY INVOLVED IN INVOLVED IN GENERAL AMINO ACID CONTROL RESPONSE BY SIMILARITY TO YEAST GCN2: Q9HDW2;Q9HGN1; [pompepV13] \|\|SPBP18G5.01\|putative serine/threonine protein kinase [pompepnew.fasta] Probable serine/threonine-protein kinase C36B7.09 (EC 2.7.1.37) [4896.FASTAC] \|\|SPBP18G5.01\|RWD domain\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] Gcn2 [Schizosaccharomyces pombe]gi\|46396516\|sp\|Q9HGN1\|KO41_SCHPO Probable serine/threonine-protein kinase C36B7.09 [nrdb_11152004_Chlamydomonas] \|gcn2\|ppk28, SPBP18G5.01\|eIF2 alpha kinase Gcn2\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Serine/threonine-protein kinase gcn2 [nr-271106-contam.fasta] Gcn2 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPBC36B7.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] eIF-2-alpha kinase GCN2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gcn2 PE=2 SV=2 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	1576 amino acids
Gene Ontology:
Cellular Component:	cytosolic ribosome [ISS]
Biological Process:	negative regulation of translational initiation in response to starvation [TAS] regulation of translational initiation in response to osmotic stress [IGI] G1/S transition checkpoint [IMP] protein amino acid phosphorylation [IDA]
Molecular Function:	ATP binding [ISS] protein homodimerization activity [ISS] eukaryotic translation initiation factor 2alpha kinase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAAKRLELC KEIQENEIEA LKAIFMDDFE ELKVRNAWNV TNGHVYCIHL CSRSANSKSI  60
   61 AKLDLCIELG RSYPYVKPVI KLQNGENVLN SQIRFLLDKL DTKAKDLLGE EMIFELASIV 120
  121 QDYLNDWQSD LSSQFASLEE ERAVQLKHDR ERAEVDLQLR LKREKDALFE EEQTLQNKIQ 180
  181 DELQRRSYET PQSSSKKKTN SKETTSLETL PTSIYFDCSI SVRDCHDSLV TFNRVLPLYT 240
  241 ISHSNLSTLT LVKPESKEIS LQDCVFLLRT VRISTPYWST EDGKREIQEL EYELESLKVI 300
  301 RHDLLASIYE YQLERETRGY GWRLYVLQEY SPKFTLFSLL QTVLTLDVET VRAFSNNILE 360
  361 GLAELHRLGI SHKSLHLDNV VLFHSGHRTF AKLMDFGFTR TLRDMNASHP FNINSQSITN 420
  421 ILPEGLYPPE VSESSFAAAS RKTDIWCFGL LVLQMLCGAH VLNKFSSLKL IMTHVIPLLP 480
  481 GSYQDLVRRC LMRDSRKRPS AIDLLSSHVI RLGTAVLPPV EQGTFSKSAR PSYGGQQDGI 540
  541 IDLLYRKSVS RYETDFEELE FLGRGGFGEV VKVKNRIDGR FYAVKKLVLL SDDKENSRIL 600
  601 REVMTLSRLH HEHVVRYYTA WVETEANDTV TEIISSDSES LSQSLNMAVD FRQSSSLPAD 660
  661 KLSSLDIHFE DDYNSSADEE DPEASDISFQ YSNTSDKEGS SDKDSSIEEA SSVKTQENGL 720
  721 NATLYIQMEY CEKLSLQDII RDKIPVDEMW RLFRQILEAL AYIHSRGMMH RDLKPGNIFL 780
  781 DENRNVKLGD FGLATENENY QDNNDKWKNR QSADEDLTTG VGTALYVAPE LLSRRNGVRY 840
  841 DAKVDMYSLG IILFEMCMTF STSMERIRII DTIRSPSISF PSTFPFSRAS HEFKVIHCLL 900
  901 QHDPTKRPSS QELLESEAIP PKVGEEFIQE GLRLLSNPNT PYYLKLLKVL FGQVPDRHKD 960
  961 FTYDFNLSEE SGVLSKVSDR GWDSLLACLV RDHVVKVFRR HGAKERESHI LFPKSSQYDK1020
 1021 DQASVSLLDK NGTLLQLPYD TVLPYARNVA RNAVEEEKTY LISDVFREAK GGGRPKAIKE1080
 1081 ISFDITTNSD NLDWYDAETI KALDEVLTEI PSLTESCILI NHADILSSIL DYLQVSKDKR1140
 1141 RMATHILGQI NQRLTLSQVR NQLRIESLVP STTLDDLSLF DFRENYEEGA SKLRKIFGKE1200
 1201 MPQKMRTALN YMERVVKLLR ALKISHQLYF MPLCVYNFEF YDGGLMFQAI NLAEKSELIC1260
 1261 AGGRYDKLVR FFDPPLMRTA RKKHVVGICF ALEKLVFSML RYIRFHNSKQ SSKHSPSPTL1320
 1321 KSVGPWAPRR VDVLVTSIGK DSILEKCSLL QELWALNIQA DIVLRGASSL EEIVTHYRSE1380
 1381 GINWVLVVRQ KNTQMEHSVK ARNILKNEDD EIRFDEVGMW LLGEINERKR NESMLQSKRI1440
 1441 LDSAQQDVAK FVDTSQSNLD VQLISLKDVN DRKYKWKHKQ NAMNKVYDLV QSAIRESSED1500
 1501 AIALAVDCDS EAMEKLRSTT TLDEESWKRL IESCPASQRE YMQRLQKKLV TLAEQDKKRV1560
 1561 WICSFRTNEI YLYGLK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: gcn2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: