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Protein Overview: eya-1

General Information:
Name(s) found: eya-1 / CE36113 [WormBase]
Description(s) found:
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  • WBGene00001377 locus:eya-1 status:Confirmed UniProt:O17670 protein_id:CAB05707.2 [WormBase]
  • gi|71982196|ref|NP_001021055.1| EYA (Drosophila eyes absent) homolog family member (eya-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|38422756|emb|CAB05707.2| C. elegans protein C49A1.4a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep115.fasta]
  • Hypothetical protein C49A1.4 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE36113 WBGene00001377 locus:eya-1 Drosophila clift protein like status:Confirmed TR:O17670 protein_id:CAB05707.2 [wormpep150.fasta]
  • 36113 WBGene00001377 locus:eya-1 Drosophila clift protein like status:Confirmed TR:O17670 protein_id:CAB05707.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Drosophila clift protein like status:Confirmed TN:CAB05707 protein_id:CAB05707.2 [wormpep115.fasta.reversed]
  • CE36113 WBGene00001377 locus:eya-1 Drosophila clift protein like status:Confirmed UniProt:O17670_CAEEL protein_id:CAB05707.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE36113 WBGene00001377 locus:eya-1 Drosophila clift protein like status:Confirmed UniProt:O17670_CAEEL protein_id:CAB05707.2| [wormORF-contam.fasta]
  • Hypothetical protein C49A1.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • EYA (Drosophila eyes absent) homolog family member (eya-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE36113 WBGene00001377 locus:eya-1 Drosophila clift protein like status:Confirmed UniProt:O17670 protein_id:CAB05707.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE36113 WBGene00001377 locus:eya-1 status:Confirmed UniProt:O17670 protein_id:CAB05707.2 [wormpep246-ecoli-contam.fasta]
  • CE36113 WBGene00001377 locus:eya-1 status:Confirmed UniProt:O17670 protein_id:CAB05707.2 Eyes absent homolog [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
  • Eyes absent homolog OS=Caenorhabditis elegans GN=eya-1 PE=3 SV=3 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 503 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: tissue morphogenesis [IGILink to PubMed article][IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IGILink to PubMed article][IMPLink to PubMed article]
    embryonic morphogenesis [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    multicellular organismal development [IEALink to PubMed article]
    negative regulation of apoptosis [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [ISSLink to PubMed article]
    transcription regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPDSEGQKL KTFLLGTGTT LDPSLDPTGN SNFSMATTSD SSTIWTALPA SQPGDKDIPT  60
   61 VDLAAISEAY GSTSSTTSLT SSVTSQYQYN SYPQYAMYTS ANPANYYQQV TANLRAGTTA 120
  121 FPYSLTTPSY YGSYPVDYTS AAAAYQNPYY TNLRGGTAAP YYNPLNATTA AAYASVASSV 180
  181 LGTDAVNLGT SSDGSTGVPS TVTSFSLKEK KPKVSKKKKT GSCSPGDETY ARVFIWDIDD 240
  241 IAVISRNYLA SVTHTNEFYA RAANSVSHLM ERIALNNFAD VNEFLEGDIT NIEDAVVDET 300
  301 TMDSGPIDNL RGLDVMRRVA PKYSAFRQFY TENSTKNDVA GFKQEQNGFN FELLERVGFG 360
  361 AREATELYQS AIQLQTLPNF GQRWPCAQRC MDLVVEKSKL SAEKYANVVL SNDGLVLGAA 420
  421 QLMISGLNSS VPVENIYSIS KQGKESVFEK IQSRFGKKCS FICITSGDTA NSAKRLNIPV 480
  481 WPLNSNTDLD KLYSALDNFL LGG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] deduced N/A No confident structure predictions are available.
    2 View Details [97..258] PSI-BLAST 5.09691 Sec24
    3 View Details [259..503] MSA 1.041944 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle