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Protein Overview: unc-75

General Information:
Name(s) found: unc-75 / CE36103 [WormBase]
Description(s) found:
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  • WBGene00006807 locus:unc-75 status:Confirmed UniProt:G5EE68 protein_id:CAB03896.4 [WormBase]
  • gi|71980775|ref|NP_492958.3| UNCoordinated family member (unc-75) [Caenorhabditis elegans] [NCBI NR]
  • gi|38422759|emb|CAB03896.4| C. elegans protein C17D12.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|33469616|gb|AAQ19851.1| putative RNA-binding protein [Caenorhabditis elegans] [NCBI NR]
  • [wormpep115.fasta]
  • putative RNA-binding protein [Caenorhabditis elegans]gi|38422759|emb|CAB03896.4| Hypothetical protein C17D12.2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed TR:O62068 protein_id:CAB03896.4 [wormpep150.fasta]
  • 36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed TR:O62068 protein_id:CAB03896.4 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed TN:CAB03896 protein_id:CAB03896.4 [wormpep115.fasta.reversed]
  • CE36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed UniProt:O62068_CAEEL protein_id:CAB03896.4 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed UniProt:O62068_CAEEL protein_id:CAB03896.4| [wormORF-contam.fasta]
  • UNCoordinated family member (unc-75) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C17D12.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • putative RNA-binding protein [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed UniProt:O62068 protein_id:CAB03896.4 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE36103 WBGene00006807 locus:unc-75 RNA recognition motif. (aka RRM, RBD, or RNP domain) (2 domains) status:Confirmed UniProt:G5EE68 protein_id:CAB03896.4 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE36103 WBGene00006807 locus:unc-75 status:Confirmed UniProt:G5EE68 protein_id:CAB03896.4 [wormpep246-ecoli-contam.fasta]
  • Putative RNA-binding protein OS=Caenorhabditis elegans GN=unc-75 PE=2 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 514 amino acids

    Gene Ontology:
    Cellular Component: nuclear speck [IDA]
    Biological Process: synaptic transmission, cholinergic [IMP]
    mRNA metabolic process [ISS]
    positive regulation of synaptic transmission, GABAergic [IMP]
    positive regulation of synaptic transmission, cholinergic [IMP]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQQHEMRA SSTSSTDSNG FPVKDPDAIK LFVGQIPRNL EEKDLRHLFE QFGKIYEFTI  60
   61 LKDKYTGMHK GCAFLTYCHR DSAVRCQATL HDQKTLPGMN RAMQVKPADT DSRPASPKDK 120
  121 MDDKKLFIGM LSKQQSEDEV RALFATFGEL DEVTVLRGAD GASKGCAFVK YKHGLDAHMA 180
  181 ISALHGSQTM PGASSSLVVK YADTEKERQN RRMQQMAAQM GMLNPMLVNQ VGMQYNAYQQ 240
  241 VLQQQSLAAQ TNAMASAAYL PLLQQQTTDP LHVLQLQAAA AAAQAAANPV LSQQTQQQQQ 300
  301 QQQQLAAQLQ LQSAAAQNPH YALAAQALAQ QQAAQQAQAV VAHSHAQVHQ HQTAQVTSTA 360
  361 SHAQTENPAA SSYGSLAAAA AAANYSSLLS GMESQHNAAA ALQLAQIQQQ AAAALPMVTP 420
  421 REVLGPDGCN LFIYHLPQEF GDAELIQMFA PFGHIVSAKV FVDRATNQSK CFGFVSYDNI 480
  481 HSSQAAITAM NGFQIGMKRL KVQLKRPRNE SRPY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] PSI-BLAST 38.221849 No description for 2dhsA was found.
    2 View Details [220..412] deduced N/A No confident structure predictions are available.
    3 View Details [413..514] PSI-BLAST 25.221849 solution structure of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle