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Protein Overview: ech-8

General Information:
Name(s) found: ech-8 / CE35450 [WormBase]
Description(s) found:
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  • WBGene00001157 locus:ech-8 status:Confirmed UniProt:O17761 protein_id:CAB02891.2 [WormBase]
  • gi|71985923|ref|NP_501876.2| Enoyl-CoA Hydratase family member (ech-8) [Caenorhabditis elegans] [NCBI NR]
  • gi|34555949|emb|CAB02891.2| C. elegans protein F01G10.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Hypothetical protein F01G10.2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Confirmed TR:O17761 protein_id:CAB02891.2 [wormpep150.fasta]
  • 35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Partially_confirmed TR:O17761 protein_id:CAB02891.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Partially_confirmed TR:O17761 protein_id:CAB02891.2 [wormpep132.fasta]
  • 35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Confirmed TR:O17761 protein_id:CAB02891.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • enoyl-CoA hydratase status:Partially_confirmed TN:CAB02891 protein_id:CAB02891.2 [wormpep115.fasta.reversed]
  • CE35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Confirmed UniProt:O17761_CAEEL protein_id:CAB02891.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Confirmed UniProt:O17761_CAEEL protein_id:CAB02891.2| [wormORF-contam.fasta]
  • Enoyl-CoA Hydratase family member (ech-8) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE35450 WBGene00001157 locus:ech-8 enoyl-CoA hydratase status:Confirmed UniProt:O17761 protein_id:CAB02891.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE35450 WBGene00001157 locus:ech-8 status:Confirmed UniProt:O17761 protein_id:CAB02891.2 [wormpep246-ecoli-contam.fasta]
  • Enoyl-CoA Hydratase OS=Caenorhabditis elegans GN=ech-8 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: fatty acid beta-oxidation multienzyme complex [IEALink to PubMed article]
    mitochondrion [IEALink to PubMed article]
    Biological Process: fatty acid beta-oxidation [IEALink to PubMed article]
    fatty acid metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity [IEALink to PubMed article]
    3-hydroxyacyl-CoA dehydrogenase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyryl-CoA epimerase activity [IEALink to PubMed article]
    enoyl-CoA hydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKVPQAVRD YLMEAHQLAA QWSLPNDRGD YINSKSIPIK SVAVIGGGTM GRGIAIAFCL  60
   61 SGFETYLVEV NNKAAEFCKN ELEITYKREK AFRRLNDSKV EKLRKNLQIT TDFQKLNNCD 120
  121 LIVEAVFEDM KLKKELFTKL DKICKPSCIF GTNTSSLDLN EMSSVLRDPT KVVGIHFFNP 180
  181 ANLIRMVEVI YGSKTSSKAV ATAFEACRSI KKLPVLVGNC PAFVFNRLLG VYLNQSQKLM 240
  241 YEYGYLPHQI DKIITNFGFL MGPLTVADMN GLDVMEKLKK ENGWPASDFE KEVWRQKRYG 300
  301 RKTNKGYYKY DPNTHKKEND IEMEQLIRKF SSAASPNIQI LNDQDAVNFL LYPMVNEGLL 360
  361 CIEEGIIHHE SLIDIMFILG FGWPVATGGP MRFGWLQGIE KVASTIILWN SLEPNDRTYK 420
  421 VAATLQNVDR KNFAAKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..437] PSI-BLAST 98.0 Crystal structure of 3-hydroxyacyl-CoA dehydrogenase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.54

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle