YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: ero-1

General Information:
Name(s) found: ero-1 / CE33847 [WormBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • WBGene00001334 locus:ero-1 Endoplasmic oxidoreductin-1 status:Confirmed UniProt:Q7YTU4 protein_id:CAC70110.4 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 478 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    FAD binding [IEALink to PubMed article]
    oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREPLLQLIV LSLIIIVVNT QFESGRLCFC KGFEAVEPCD CSKPQTIDKL NNHRIYEKVQ  60
   61 KLLKKDFFRF YKVNMDKTCP FWADDRQCGT NQCGIAFCDD EVPAGLRRRN AVNMEAAAVK 120
  121 EEEDDDAEKC ADAGNNIDPM DRTLHDDEKR QLDAMDHHDD GLEDKFCEIE DDESDGMHYV 180
  181 DLSKNPERYT GYAGKSPQRV WKSIYEENCF KPDPKFDKNF LTNPSNFGMC LEKRVFYRLI 240
  241 SGLHSAITIS IAAYNYKPPP PSLGQFGSQM GTWFRNTEMF AGRFGTKWSW EGPQRLRNVY 300
  301 FIYLLELRAL LKAAPYLQNE LFYTGNDVED AETRKAVEDL LEEIRAYPNH FDESEMFTGV 360
  361 ESHARALREE FRSHFVNISR IMDCVECDKC RLWGKVQTHG MGTALKILFS DLPHSHYKQD 420
  421 SSKFQLTRNE VVALLQSFGR YSSSILEVDN FREDMYPGES VMNTAADGPP RKSNKIDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..478] PSI-BLAST 112.0 Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on sulfur group of donors
    		•  3.04541306149882 bayes_pls_golite062009
  • thiol oxidase activity
    		•  1.56067935587779 bayes_pls_golite062009
  • binding
    		•  1.51315006963036 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor
    		•  1.31287436426921 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  1.25764823859811 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.21113889423637 bayes_pls_golite062009
  • catalytic activity
    		•  1.09506175640279 bayes_pls_golite062009
  • protein binding
    		•  0.524855475418758 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  0.384901602591813 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle