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Protein Overview: daf-4

General Information:
Name(s) found: daf-4 / CE33555 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00000900 locus:daf-4 status:Confirmed UniProt:G8JY02 protein_id:CCD63120.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 446 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of BMP signaling pathway [IMPLink to PubMed article]
    positive regulation of BMP signaling pathway [IMPLink to PubMed article]
    dauer larval development [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    growth factor binding [IPILink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]
    transmembrane receptor protein serine/threonine kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQKGTVRLK ALVLICLPLF LIATPVPVAV TEDDRQDRIE SEAAEKEWAN TLVSKVAQSN  60
   61 GTGTIKVSAP AKPTLRRMDN EEDEVISIEC VYYDEMECEK SGDCEITKKT CYSEAHLKAV 120
  121 GCLAVFGLPT QEINSTEPYL KVDKPQYKSL GCMPYQHADS MNCENESSCR QGRSFRGGIG 180
  181 MCCCSTNNCN MPDLIEMVNP SLKKDSDNSA LLWASTPSNM DLESLDKFPF YWIIIIALSV 240
  241 ILCIALLILA YVGWKFQQNK KEEIKKQQKI KFDMEKTDAL EAGNVPLVEP EEEMIEMVET 300
  301 PKELPITDFQ LISKGRFGKV FKAQYTPDSG EKRLVAVKKL NEFQKASFLA EKRIFDELNE 360
  361 YPKWYKSIVE FVCAEKIGDE YWIVTEFHER LSLYELLKNN VISITSANRI IMSMIDGLQF 420
  421 LHDDRPYFFG HPKKPIIHRL VENENN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 24.0 Crystal structure of ErbB4/HER4 extracellular domain
    2 View Details [257..446] PSI-BLAST 32.69897 No description for 2qoqA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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