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Protein Overview: nac-2

General Information:
Name(s) found: nac-2 / CE33536 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003518 locus:nac-2 Sodium-dependent high-affinity dicarboxylate transporter 2 status:Confirmed UniProt:P32739 protein_id:CAA78468.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    lipid metabolic process [IMPLink to PubMed article]
    citrate transport [IDALink to PubMed article][IEALink to PubMed article]
    succinate transport [IDALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: citrate transmembrane transporter activity [IDALink to PubMed article][IEALink to PubMed article]
    succinate transmembrane transporter activity [IDALink to PubMed article]
    transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPSPQRTLI KKLLVLLGPL VAVPLLFFGP EYRCLFSIIF LSTYWIGEAF PIGVTSLFPL  60
   61 ALYPILQIVP SKQISPVYFK DSIVLFMCTL IMAMAVEATG LHRRIALKLL TKVGAKQPVM 120
  121 LLGFMCITSF ISFFVSDTAC TALMCPTAVA LLMSMSDAVQ HLKEDHRKPK PPPDDATVAE 180
  181 KLRIDDMTPQ DAGFCKALIL ACAHASLIGG TAIITSTGPN LVFRENIHKR YPEGQVTMTY 240
  241 LQWMVFAIPP MFVYLLASYI ILVCYFMGPS TFARWFERPS KEEAHLKKLI EKNIQTMYED 300
  301 LGDVSWGEKS VFVFFILLIG SWISRDPGFT PGWGDLLPHR NFISDSVSGV LISCILFVWP 360
  361 KDPFDPIDPM APILKWTDMK SKFSWSCTLL IGAGYAISEG VDKSGLSRLI SCGMKNIFVG 420
  421 MSSLPLQLTV TTIIVIMTEF ASNVSTGSIF IPISLGVAES MGVHPLYLAL PTTVACSFAF 480
  481 MLPISTPPNA VVYDTKVISM VEMIVCGFLL NIACILITSL NMNTWTYFIF SLNIFPENIV 540
  541 ISSENSSYPV C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..162] MSA 5.380994 View MSA. No confident structure predictions are available.
    2 View Details [163..339] deduced N/A No confident structure predictions are available.
    3 View Details [340..551] MSA 5.505997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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