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Protein Overview: nac-3

General Information:
Name(s) found: nac-3 / CE33531 [WormBase]
Description(s) found:
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  • WBGene00003519 locus:nac-3 Sodium-dependent high-affinity dicarboxylate transporter 3 status:Confirmed UniProt:Q21339 protein_id:CAA83225.3 [WormBase]
  • gi|71988385|ref|NP_001022673.1| NADC (Na+-coupled dicarboxylate transporter) family member (nac-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|45645187|sp|Q21339.3|NAD3_CAEEL RecName: Full=Sodium-dependent high-affinity dicarboxylate transporter 3; AltName: Full=Na(+)/dicarboxylate cotransporter 3; Short=NaDC-3; Short=ceNaDC3 [NCBI NR]
  • ref|NP_499253.2| na+-coupled DiCarboxylate transporter, high-affinity plasma membrane transporter INDY2 (62.3 kD) (nad-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|29292178|emb|CAA83225.3| C. elegans protein K08E5.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|28458811|gb|AAM11894.1| high-affinity plasma membrane transporter INDY2 [Caenorhabditis elegans] [NCBI NR]
  • Sodium-dependent high-affinity dicarboxylate transporter 3 OS=Caenorhabditis elegans GN=nac-3 PE=2 SV=3 [Swiss-Prot]
  • (Q21339) Sodium-dependent high-affinity dicarboxylate transporter 2 (Na(+)/dicarboxylate cotransporter 2) (NaDC-2) (ceNaDC2) [Swiss-Prot]
  • [wormpep104.fasta]
  • CE33531 WBGene00003519 locus:nac-3 Yeast ORF YCR37C status:Confirmed SW:Q21339 protein_id:CAA83225.3 [wormpep150.fasta]
  • 33531 WBGene00003519 locus:nac-3 Yeast ORF YCR37C status:Confirmed SW:Q21339 protein_id:CAA83225.3 [wormpep130-phg-ecoli-orf-rand.fasta]
  • na+-coupled DiCarboxylate transporter, high-affinity plasma membrane transporter INDY2 (62.3 kD) (nad-2) [Caenorhabditis elegans]gi|29292178|emb|CAA83225.3| Hypothetical protein K08E5.2a [Caenorhabditis elegans]gi|28458811|gb|AAM11894.1| high-affinity p [nrdb_11152004_Chlamydomonas]
  • locus:nad-2 Yeast ORF YCR37C status:Confirmed TN:CAA83225 protein_id:CAA83225.3 [wormpep115.fasta.reversed]
  • CE33531 WBGene00003519 locus:nac-3 Yeast ORF YCR37C status:Confirmed UniProt:Q21339 protein_id:CAA83225.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33531 WBGene00003519 locus:nac-3 Yeast ORF YCR37C status:Confirmed UniProt:Q21339 protein_id:CAA83225.3| [wormORF-contam.fasta]
  • Sodium-dependent high-affinity dicarboxylate transporter 3 (Na(+)/dicarboxylate cotransporter 3) (NaDC-3) (ceNaDC3) [nr-271106-contam.fasta]
  • high-affinity plasma membrane transporter INDY2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • NADC (Na+-coupled dicarboxylate transporter) family member (nac-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein K08E5.2a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33531 WBGene00003519 locus:nac-3 status:Confirmed UniProt:Q21339 protein_id:CAA83225.3 Sodium-dependent high-affinity dicarboxylate transporter 3 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 566 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    citrate transport [IEALink to PubMed article]
    succinate transport [IDALink to PubMed articleLink to PubMed article]
    Molecular Function: citrate transmembrane transporter activity [IEALink to PubMed article]
    high affinity sodium:dicarboxylate symporter activity [IDALink to PubMed article]
    succinate transmembrane transporter activity [IDALink to PubMed articleLink to PubMed article]
    transporter activity [IEALink to PubMed article]
    arsenite transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSLHLSGW PENSESRQRM LESSSSTNFV QHFVSREISN KERLLSLFRR LRNGLVLVLT  60
   61 PLFFGQMLNW EGPEWKCAYC VCIIAVYWMS EVMPLAVTAM LPVVLFPLVG VLDANTTAKE 120
  121 YMNDTNFLFI GGLIMAAAVE KCDLHERVAL SVLRCVGSEP KWIMLGFMTV TALLSSFISN 180
  181 TATTAMMVPI GQSVVQQLIS SFQHHPTNGE RGRLGCKKMA TGLVLSICFA ANIGGTGTAT 240
  241 GTPSNLVMLG QLSALFPKVD GSLNYVTWIF FAYPLMLLCL FVAWMTLVSF FLRDAPEKDE 300
  301 AVTEMLKTRY NELPRMTYAE KSVFVCFCIL LSLWVFRNPG VVPGFGVFFK KGAYTDATSA 360
  361 MIVAFLLFVL PSERPDLATY IKKEDLKKRG CLMDWKTMQE TFPWSVVLLL GGGFALAAGV 420
  421 KESGLSLLIG NSLSSIEHLP LWILQLLTML IAMVITNICS NTVTASIFVP IVATLAQRAG 480
  481 HHPFTLMLPT TLASSFAFIF PVGTPPNAIV FGSGMVKVSD MAFVGGIISL ELLVLTVLYM 540
  541 NSIAYLTLPL LEFPTWAIIA NSTMQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] MSA 4.615993 View MSA. No confident structure predictions are available.
    2 View Details [206..344] deduced N/A No confident structure predictions are available.
    3 View Details [345..566] MSA 18.677997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle