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Protein Overview: syd-1

General Information:
Name(s) found: syd-1 / CE33392 [WormBase]
Description(s) found:
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  • WBGene00006363 locus:syd-1 Rho GTPase-activating protein syd-1 status:Confirmed UniProt:Q86NH1 protein_id:CCD70507.1 [WormBase]
  • gi|71988432|ref|NP_001022148.1| SYnapse Defective family member (syd-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|28275150|gb|AAO38645.1| Synapse defective protein 1, isoform c, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • Synapse defective protein 1, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed TR:Q86NH0 protein_id:AAO38645.1 [wormpep150.fasta]
  • 33392 WBGene00006363 locus:syd-1 status:Partially_confirmed TR:Q86NH0 protein_id:AAO38645.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE33392 WBGene00006363 locus:syd-1 status:Partially_confirmed TR:Q86NH0 protein_id:AAO38645.1 [wormpep132.fasta]
  • 33392 WBGene00006363 locus:syd-1 status:Confirmed TR:Q86NH0 protein_id:AAO38645.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:syd-1 status:Partially_confirmed TR:Q86NH0 protein_id:AAO38645.1 [wormpep115.fasta.reversed]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed UniProt:SYD1_CAEEL protein_id:AAO38645.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed UniProt:SYD1_CAEEL protein_id:AAO38645.1| [wormORF-contam.fasta]
  • SYnapse Defective family member (syd-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed UniProt:Q86NH1 protein_id:AAO38645.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed UniProt:Q86NH1 protein_id:CCD70507.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE33392 WBGene00006363 locus:syd-1 status:Confirmed UniProt:Q86NH1 protein_id:CCD70507.1 Rho GTPase-activating protein syd-1 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q86NH1, Isoform c of Rho GTPase-activating protein syd-1 OS=Caenorhabditis elegans GN=syd-1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 721 amino acids

    Gene Ontology:
    Cellular Component: presynaptic membrane [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: locomotion [IGILink to PubMed article]
    signal transduction [IEALink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNATTSSTL RTHASTSSPR NHFAPRLVNG HSHSIGVPSA STTSHDHQYQ RFASEPSDSV  60
   61 SRTARVPPPR LASATVRRTE SFNSAPGVST SAPMYTLPRS STAVPPPDIL GSIPYSARDP 120
  121 LMRSSADLPY DPMTGRLSSS VPTDPLLSRS LCSPILPRTL RQANDSNKSN SLPRRRIMTG 180
  181 GRNVKWRNDV VSTSDLCGEE SDGAISAPEY SSPPFSRLTQ QQQFRLSNGS PGRTVNDIFS 240
  241 AAEYRNWAGP YDPRGMYGPF PPGQRATRWS HTYGEQRAPR TSSLPGRTVL AQSLVGSPVL 300
  301 PRHPPPIVQD RPSAVFDRYH VSPLMNRRAP LRAAGPGINV DRLSVSSLTG ILYVHIVEGR 360
  361 GLKIPEKQKG LTEEMYCVLE VDEQHRARTG VSTIEQKFKW RETFHIDVVN ATVSNFFVYS 420
  421 WHPQFRHKLC HKGSLKLLEA FVVDQLNDDR VFALNLEPRG QLIVRIGFHD LQAVFRRTVN 480
  481 PRLNGVFGIS LSRLVQRERR DTPIVLTRLI QEIEKRGVDY SGLYVLCGSV EKKKMLRAEL 540
  541 ESNPLGTELA AESIPDTNVI ACLIKDFLRE LPEPLISPQI HGMLLEAASV ALPNDVQTNR 600
  601 HLVLKIIDCL QLSAKNCLLL VLDHLSTVLC SSPHNGLTPT RLSLIFAPLL FFCLDTFSPY 660
  661 TISPTSKMAA VRTLDINQAS SSLQMILSIW PSRVNSESGS DSPATTCQKG GVIAYVSESQ 720
  721 C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] MSA 4.185995 View MSA. No confident structure predictions are available.
    2 View Details [211..721] PSI-BLAST 69.221849 Crystal Structure of the Human Beta2-Chimaerin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • enzyme activator activity
    		•  0.53004209819211 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.528693496432149 bayes_pls_golite062009
  • binding
    		•  0.0980674097362609 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  0.0454578418356197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle