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Protein Overview: obr-4

General Information:
Name(s) found: obr-4 / CE32814 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00016331 locus:obr-4 Oxysterol-binding protein status:Confirmed UniProt:Q8I7N6 protein_id:CCD61907.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 400 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid metabolic process [IEALink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDEDGYDF GDSNEDFDEI YNNAEEHDIG NVQQDHGSVL MHLLSQVSVG MDLTKVTLPT  60
   61 FILERRSLLE MYADFFAHPD LFIATNGNDS AEKRMIAVVR YYLNSFYAAR KSGVAKKPYN 120
  121 AILGETFRCR YSVPNSSLSG KKTESGPWPG SDEKQLTFIA EQVSHHPPIS AFYAEMPSEG 180
  181 ISFNAHIYTK SSFLGLSIGV ASIGEGILTL HNYGDEQYTI TFPSGYGRSI MSTPWFEFGG 240
  241 KVKVECEKTG YRADIEFLTK PFFGGKPHRI QGSICRDGAK KPVLTLRGEW NGTMYAKTQN 300
  301 GEEYVFVDVK AKPEVKKECV PVMQQGKRES RRLWRHVTAA LLRNRIQTAT TSKRFIEQRQ 360
  361 RKEAKERLES GEKWTPLLFD TTDKDGEWMY KQKFGVRKAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..400] PSI-BLAST 79.39794 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxysterol binding
    		•  5.62675037461468 bayes_pls_golite062009
  • sterol binding
    		•  4.18891468109664 bayes_pls_golite062009
    		• 3.02967613614595 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • phosphoinositide binding
    		•  2.2725849852584 bayes_pls_golite062009
  • binding
    		•  2.10831141109811 bayes_pls_golite062009
  • phospholipid binding
    		•  2.08170907241909 bayes_pls_golite062009
  • lipid binding
    		•  1.8520231230392 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.72950454023501 bayes_pls_golite062009
  • cholesterol binding
    		•  0.644339278395346 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle