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View Structure Prediction Details

Protein: obr-4
Organism: Caenorhabditis elegans
Length: 400 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for obr-4.

Description E-value Query
Range
Subject
Range
obr-4 - oxysterol-binding protein status:Confirmed UniProt:O01686 protein_id:AAC24270.1
437.0 [0..1] [400..277]

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Predicted Domain #1
Region A:
Residues: [1-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDEDGYDF GDSNEDFDEI YNNAEEHDIG NVQQDHGSVL MHLLSQVSVG MDLTKVTLPT  60
   61 FILERRSLLE MYADFFAHPD LFIATNGNDS AEKRMIAVVR YYLNSFYAAR KSGVAKKPYN 120
  121 AILGETFRCR YSVPNSSLSG KKTESGPWPG SDEKQLTFIA EQVSHHPPIS AFYAEMPSEG 180
  181 ISFNAHIYTK SSFLGLSIGV ASIGEGILTL HNYGDEQYTI TFPSGYGRSI MSTPWFEFGG 240
  241 KVKVECEKTG YRADIEFLTK PFFGGKPHRI QGSICRDGAK KPVLTLRGEW NGTMYAKTQN 300
  301 GEEYVFVDVK AKPEVKKECV PVMQQGKRES RRLWRHVTAA LLRNRIQTAT TSKRFIEQRQ 360
  361 RKEAKERLES GEKWTPLLFD TTDKDGEWMY KQKFGVRKAV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.39794
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxysterol binding 5.62675037461468 bayes_pls_golite062009
sterol binding 4.18891468109664 bayes_pls_golite062009
3.02967613614595 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
phosphoinositide binding 2.2725849852584 bayes_pls_golite062009
binding 2.10831141109811 bayes_pls_golite062009
phospholipid binding 2.08170907241909 bayes_pls_golite062009
lipid binding 1.8520231230392 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.72950454023501 bayes_pls_golite062009
cholesterol binding 0.644339278395346 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle