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Protein Overview: obr-4

General Information:
Name(s) found: obr-4 / CE08539 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00016331 locus:obr-4 Oxysterol-binding protein status:Confirmed UniProt:O01686 protein_id:CCD61906.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 676 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid metabolic process [IEALink to PubMed article]
    Molecular Function: calmodulin binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGPLSKWTN MVHGWQYRWF KIENDTLLYY TSREKMLKGQ QRGQIRLTGA VVGIDGENNS  60
   61 LFTITVEGKT FHMQGRDLRE RNQWVRILEN SIRASSGYAK NVSVGTTPSQ HFKQRTEEAN 120
  121 EFLKTLVEKV KALEQLKSGE RAVDEKKTID SLIAASNNLT NNVKHAIIYL QMAQARLDPN 180
  181 MKTEKLMFTH PDLNEKPSSR ETPGTVSDST QTSTDKPISG IQHLDHLKPQ RAESYASSDE 240
  241 EEFYDADEEL IDLDNFESEK SGQESGDSNR TSDAAIMSSD EDGYDFGDSN EDFDEIYNNA 300
  301 EEHDIGNVQQ DHGSVLMHLL SQVSVGMDLT KVTLPTFILE RRSLLEMYAD FFAHPDLFIA 360
  361 TNGNDSAEKR MIAVVRYYLN SFYAARKSGV AKKPYNAILG ETFRCRYSVP NSSLSGKKTE 420
  421 SGPWPGSDEK QLTFIAEQVS HHPPISAFYA EMPSEGISFN AHIYTKSSFL GLSIGVASIG 480
  481 EGILTLHNYG DEQYTITFPS GYGRSIMSTP WFEFGGKVKV ECEKTGYRAD IEFLTKPFFG 540
  541 GKPHRIQGSI CRDGAKKPVL TLRGEWNGTM YAKTQNGEEY VFVDVKAKPE VKKECVPVMQ 600
  601 QGKRESRRLW RHVTAALLRN RIQTATTSKR FIEQRQRKEA KERLESGEKW TPLLFDTTDK 660
  661 DGEWMYKQKF GVRKAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 15.39794 No description for 2d9xA was found.
    2 View Details [108..268] deduced N/A No confident structure predictions are available.
    3 View Details [269..676] PSI-BLAST 71.221849 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • oxysterol binding
    		•  5.62675037461468 bayes_pls_golite062009
  • sterol binding
    		•  4.18891468109664 bayes_pls_golite062009
    		• 3.02967613614595 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  2.53764463034371 bayes_pls_golite062009
  • phosphoinositide binding
    		•  2.2725849852584 bayes_pls_golite062009
  • phospholipid binding
    		•  2.08170907241909 bayes_pls_golite062009
  • lipid binding
    		•  1.8520231230392 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.72950454023501 bayes_pls_golite062009
  • cholesterol binding
    		•  0.644339278395346 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle