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Protein Overview: nhr-49

General Information:
Name(s) found: nhr-49 / CE32694 [WormBase]
Description(s) found:
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  • WBGene00003639 locus:nhr-49 Nuclear hormone receptor family member nhr-49 status:Confirmed UniProt:O45666 protein_id:CAD57703.1 [WormBase]
  • gi|32563637|ref|NP_871799.1| Nuclear Hormone Receptor family member (nhr-49) [Caenorhabditis elegans] [NCBI NR]
  • gi|25814794|emb|CAD57703.1| C. elegans protein K10C3.6d, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed SW:O45666 protein_id:CAD57703.1 [wormpep150.fasta]
  • 32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed TR:Q8I4H3 protein_id:CAD57703.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • nuclear Hormone Receptor (nhr-49) [Caenorhabditis elegans]gi|25814794|emb|CAD57703.1| Hypothetical protein K10C3.6d [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed TR:Q8I4H3 protein_id:CAD57703.1 [wormpep132.fasta]
  • 32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed SW:O45666 protein_id:CAD57703.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed TR:Q8I4H3 protein_id:CAD57703.1 [wormpep115.fasta.reversed]
  • CE32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed UniProt:O45666 protein_id:CAD57703.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32694 WBGene00003639 locus:nhr-49 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) status:Confirmed UniProt:O45666 protein_id:CAD57703.1| [wormORF-contam.fasta]
  • Nuclear Hormone Receptor family member (nhr-49) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein K10C3.6d [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32694 WBGene00003639 locus:nhr-49 status:Confirmed UniProt:O45666 protein_id:CAD57703.1 Nuclear hormone receptor family member nhr-49 [wormpep246-ecoli-contam.fasta]
  • Isoform of O45666, Isoform d of Nuclear hormone receptor family member nhr-49 OS=Caenorhabditis elegans GN=nhr-49 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 486 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNLQMIVIM DLVDPLAEPC AVCGDKSTGT HYGVISCNGC KGFFRRTVLR DQKFTCRFNK  60
   61 RCVIDKNFRC ACRYCRFQKC VQVGMKREAI QFERDPVGSP TSGASLNGTP FKKDRSPGYE 120
  121 NGNSNGVGSN GMGQENMRTV PQSSSVIDAL MEMEARVNQE MCNRYRRSQI FANGSGGSNG 180
  181 NDTDIQQGSD SGASAFAPPN RPCTTEVDLN EISRTTLLLM VEWAKTINPF MDLSMEDKII 240
  241 LLKNYAPQHL ILMPAFRSPD TTRVCLFNNT YMTRDNNTDL NGFAAFKTSN ITPRVLDEIV 300
  301 WPMRQLQMRE QEFVCLKALA FLHPEAKGLS NSSQIMIRDA RNRVLKALYA FILDQMPDDA 360
  361 PTRYGNILLL APALKALTQL LIENMTLTKF FGLAEVDSLL SEFILDDIND HSTAPVSLQQ 420
  421 HLSSPTTLPT NGVSPLNPAG SVGSVSSVSG ITPTGMLSAT LAAPLAIHPL QSQDSILNSE 480
  481 QNNHML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 27.69897 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [136..486] PSI-BLAST 45.69897 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle