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Protein Overview: bpl-1

General Information:
Name(s) found: bpl-1 / CE32624 [WormBase]
Description(s) found:
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  • WBGene00000259 locus:bpl-1 status:Confirmed UniProt:G5EFB4 protein_id:CCD66052.1 [WormBase]
  • gi|46452280|gb|AAS98223.1| biotin protein ligase, holocarboxylase synthetase (62.5 kD) alternative variant d [Caenorhabditis elegans] [NCBI NR]
  • gi|46452278|gb|AAS98222.1| biotin protein ligase, holocarboxylase synthetase (62.5 kD) alternative variant c [Caenorhabditis elegans] [NCBI NR]
  • gi|32563944|ref|NP_871921.1| Biotin Protein Ligase family member (bpl-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|24943026|gb|AAN65328.1| Hypothetical protein F13H8.10c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32624 WBGene00000259 locus:bpl-1 status:Confirmed TR:Q8IG26 protein_id:AAN65328.1 [wormpep150.fasta]
  • 32624 WBGene00000259 locus:bpl-1 status:Confirmed TR:Q8IG26 protein_id:AAN65328.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • holocarboxylase synthetase (62.6 kD) (2G569) [Caenorhabditis elegans]gi|24943026|gb|AAN65328.1| Biotin protein ligase protein 1, isoform c [Caenorhabditis elegans]gi|46452280|gb|AAS98223.1| biotin protein ligase, holocarboxylase synthetase (62.5 kD) alt [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q8IG26 protein_id:AAN65328.1 [wormpep115.fasta.reversed]
  • CE32624 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG26_CAEEL protein_id:AAN65328.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32624 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG26_CAEEL protein_id:AAN65328.1| [wormORF-contam.fasta]
  • biotin protein ligase, holocarboxylase synthetase (62.5 kD) alternative variant d [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • biotin protein ligase, holocarboxylase synthetase (62.5 kD) alternative variant c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Biotin Protein Ligase family member (bpl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Biotin protein ligase protein 1, isoform c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE32624 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:Q8IG26 protein_id:AAN65328.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE32624 WBGene00000259 locus:bpl-1 status:Confirmed UniProt:G5EFB4 protein_id:CCD66052.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q9BI98, Biotin Protein Ligase OS=Caenorhabditis elegans GN=bpl-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein modification process [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    biotin-[acetyl-CoA-carboxylase] ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCKPNSVLVY TGGNDSLYSD IRHRLSFLLP PDEITVFNVS IQALKKQPWA EKSTVCVILA  60
   61 STNDLDDEAW EKIQAYFNQN GKIIFVCQNK LLASITGCDS SKANASILRF AFGSQNNKLK 120
  121 DTNKEFVKFL EKNMKKLPKS TAINETFRSK DVSVGANFTV VLKKEPDAPL FLYMQNNGSL 180
  181 HASALFSDAT TQQLIAPNSN LLKDSLRSVG VNVCDTTMPP LTKGILIAEY DSIIESIAGL 240
  241 RLGEEIGLQP RILLRKSDVV EELGLPEATE KLLPIEVVNR DSDAGTSKNF DFNLYFEQIH 300
  301 SKIGQVVLLV DVATTTMDII ESVNAGIPSL ESVVVIANRQ ISGRGRGGNE FLCPRGMAMF 360
  361 NFSFSISKKS RIAKHLPILQ HIFCVALVEA ARNLSGYPEF PLHIKWPNDL YCERSHKVGG 420
  421 MLLQCSTRDD SFRVSIGCGM NVSNDKPTMC LNDMLPKEAE TRITKEQLIA ETINKFTYYM 480
  481 KDYEDNGPET FKKKYHEYWL HSQQEVLLSD FNERVTIRGI DDDGYLQVRS KSNPDKIFSI 540
  541 GDDGNTFDMM KGLIRHKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] MSA 2.046978 View MSA. No confident structure predictions are available.
    2 View Details [117..210] deduced N/A No confident structure predictions are available.
    3 View Details [211..558] PSI-BLAST 78.39794 THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  3.03334029653525 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  3.03334029653525 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  3.0330284950777 bayes_pls_golite062009
  • ligase activity
    		•  2.57747899218361 bayes_pls_golite062009
  • catalytic activity
    		•  2.36416267096403 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle